Day 24 (Monday, August 16): Maryland Heights, Missouri to Carlinville, Illinois—We are in the 4th Quarter!

Yay, we're in Illinois!

We made it to Illinois today; we are getting closer and closer to the Dome! As Coach Parseghian would put it, we are in the 4th quarter. We were so excited to see signs for Chicago today. It was a beautiful sunny day, and temperatures were reasonable (finally). A bit of a headwind accompanied us for most of the day, but otherwise it was perfect for riding. We crossed the Mississippi River today as we crossed the Missouri-Illinois boarder. We were very excited to see the “Welcome to Illinois” sign, because now we know we are close! Apart from a great riding day, the only thing to report is that there was a lot of corn in Illinois (miles and miles of it). Tomorrow we head to Springfield where we have a Notre Dame club gathering.

Corn galore everywhere you look

Renate by one of the many, many farms we passed in Illinois

I wish to follow up on my yesterday’s comments about drug discovery research. The exiting drug discovery and therapeutics development in the College of Science draw significant support from several state-of-the-art core facilities on campus, including the Mass Spectrometry and Proteomics Facility, ND Integrated Imaging Facility, and the Genomics and Bioinformatics facilities. The Chemical Genomics and Drug Discovery team is currently planning a Chemical Synthesis Facility that will provide much-needed chemical support services to the University’s biomedical researchers and their external academic and industry collaborators.

The overarching vision is that the Chemical Synthesis Facility staff will provide the synthesis of small molecules for use in hit verification, lead development, and scale-up. In addition, the facility will provide expertise in the preparation of biological probes, active pharmaceutical agents as experimental controls, and small chemical libraries for structure-activity relationships and optimization of pharmacological properties. This shared user research core will also house a suite of instruments and equipment necessary to organize the products of past, current, and future chemical synthesis to create the Notre Dame Chemical Compound Collection and promote cross-disciplinary collaboration. Beyond small molecule medicinal chemistry, the new facility will be a valuable resource for collaborative research across many fields, including nanotechnology and sustainable energy research, such as materials chemistry and catalysis development.

Go Irish.

8 Comments so far

  1.    David Hyde on August 17th, 2010

    Greg and Renate,

    It is great to see that you two are nearing the end of your exciting trip. It is wonderful to see that you are raising the awareness of the exciting opportunities and progress that is being made in Notre Dame’s College of Science. I would guess that this experience will have a long-lasting impact on both of you. We are all looking forward to your return and hearing about your adventures in more detail.

  2.    Peggy Queen on August 17th, 2010

    You are in the area that I grew up – wonder people there. I’m glad the heat and humidity have subsided. Can’t wait to greet you on Notre Dame Avenue! Bike safe!!!!!!

  3.    Peggy Queen on August 17th, 2010

    You are in the area that I grew up – wonderful people there. I’m glad the heat and humidity have subsided. Can’t wait to greet you on Notre Dame Avenue! Bike safe!!!!!!

  4.    Sean Caveny on August 17th, 2010

    It was wonderful to meet the both of you last night. From the photos I see you came very close to my home. Hope you enjoyed the scenery. Take care and God Bless.

    Sean Caveny

  5.    Elizaabeth Hasse on August 18th, 2010

    Hi Greg and Renate,

    It is hard to believe that you are almost home. We cannot wait to see you on the 23rd.

    I came across a quote from Ernest Hemingway that seems appropriate given your last few days navigating the hills of Missouri:

    It is by riding a bicycle that you learn the contours of a country best, since you have to sweat up the hills and coast down them. Thus you remember them as they actually are, while in a motor car only a high hill impresses you, and you have no such accurate remembrance of country you have driven through as you gain by riding a bicycle. — Ernest Hemingway

  6.    Ani Aprahamian on August 18th, 2010

    Almost done! Very impressed with you two! See you on Monday!


  7.    Allen Utterback on August 18th, 2010

    Hi Greg & Renate, You’re in the home stretch. What an adventure. Looking forward to seeing the finish next Monday and welcoming you back! Keep plugging away!