Suarez, CD, Badve, SS, Sparano, JA, Kaliney, W, Littlepage, LE. “The AKT inhibitor triciribine in combination with paclitaxel has order-specific efficacy against Zfp217-induced breast cancer chemoresistance” Oncotarget. (In Press)

Coughlin, TR, Romero-Moreno, R., Mason, D.E., Nystrom, L., Boerckel, J.D., Niebur, GL, and Littlepage, LE. (2016) “Bone: A Fertile Soil for Cancer Metastasis” Current Drug Targets. (In Press)

Richards KE, Zeleniak AE, Fishel ML, Wu J, Littlepage LE, Hill R. (2016) Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells. Oncogene. Sep 26. PMID:27669441

Sawe, RT, Kerper, Badve, S, Li, J, Sandoval-Cooper, M, Xie, S, Shi, Z, Patel, K, Chumba, D, Properi, JR, Taylor, K, Stack, S, Mining, SK, Littlepage, LE. (2016) “Breast cancer in western Kenya is aggressive with early onset, high proliferation, and immune cell infiltration with suppression of the adaptive immune response” BMC Cancer. Mar 10;16(1):204. PMID: 26964534

Suarez, CD and Littlepage, LE. (2016) “Patient-Derived Tumor Xenograft Models of Breast Cancer” Methods Mol Biol.;1406:211-23. PMID: 26820959

Frietze S*, O’Geen H*, Littlepage LE, Simion C*, Sweeney CA*, Farnham PJ*, Krig SR*. (2014) Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with ERalpha. BMC Genomics. Jun 24;15:520. PMID: 24962896

Kessenbrock K*, Dijkgraaf GJ*, Lawson DA*, Littlepage LE, Shahi P*, Pieper U*, Werb Z.* (2013) A Role for Matrix Metalloproteinases in Regulating Mammary Stem Cell Function via the Wnt Signaling Pathway. Cell Stem Cell. Sep 5;13(3):300-13. Epub 2013 Jul 18. PMID: 23871604 (Kessenbrock and Dijkgraaf are joint first authors.)

Littlepage, L.E., Adler, A.S., Kouros-Mehr, H., Huang, G., Chou, J., Krig, S.R., Griffith, O.L., Korkola, J.E., Qu, K., Lawson, D.A., Xue, Q., Sternlicht, M.D., Dijkgraaf, G.J.P., Yaswen, P., Rugo, H.S., Sweeney, C.A., Collins, C.C., Gray, J., Chang, H.Y., Werb, Z. (2012) “The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression” Cancer Discovery; Jul;2(7):638-51. Epub 2012 May 10.

Littlepage, LE, Sternlicht, MD, Rougier, N, Phillips, J, Gallo, E, Yu, Y, Williams, K, Brenot, A, Gordon, J, Werb, Z (2010) Matrix Metalloproteinases Contribute Distinct Roles in Neuroendocrine Prostate Carcinogenesis, Metastasis, and Angiogenesis Progression. Cancer Res. Mar 15;70(6):2224-34. Epub 2010 Mar 9.

Kouros-Mehr, H, Bechis, SK, Slorach, EM, Littlepage, LE, Egeblad, M, Ewald, AJ, Pai, SY, Ho, IC, Werb, Z  (2008) GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell. Feb;13(2):141-52.

Adler, AS, Littlepage, LE, Lin, M, Kawahara, TLA, Wong, DJ, Liu, H, Werb, Z, Chang , HY (2008) CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression. Cancer Res. Jan 15;68(2):506-15.

Egeblad, M, Littlepage, LE, Werb, Z (2005) The fibroblastic coconspirator in cancer progression. Cold Spring Harb Symp Quant Biol. 2005;70:383-8. Review.

Radisky, DC, Levy, DD, Littlepage, LE, Liu, H, Nelson, CM, Fata, JE, Leake, D, Godden, EL, Albertson, DG, Nieto, MA, Werb, Z, Bissell, MJ (2005) Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability. Nature. Jul 7; 436(7047): 123-7.

Littlepage, LE, Egeblad, M, Werb, Z (2005) Coevolution of cancer and stromal cellular responses. Cancer Cell. Jun; 7(6): 499-500.

Crane, R, Gadea, B, Littlepage, L, Wu, H, Ruderman, JV (2004) Aurora A, meiosis and mitosis. Biol Cell. Apr; 96(3):215-29. Review.

Littlepage, LE, Wu, H, Andresson, T, Deanehan, JK, Amundadottir, L, Ruderman, JV (2002) Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A. Proc Natl Acad Sci U S A. Nov 26; 99(24): 15440-5.

Littlepage, LE and Ruderman, JV (2002) Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit. Genes & Dev. Sept. 1; 16(17): 2274-85.

Huang, JN, Park, I, Ellingson, E, Littlepage, LE, Pellman, D (2001) Activity of the APC (Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p.  J Cell Biol. Jul 9; 154(1): 85-94.

Mendez, R, Hake, LE, Andresson, T, Littlepage, LE, Ruderman, JV, Richter, JD (2000) Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA. Nature. 404(6775): 302-7.

Pasternack, LB, Littlepage, LE, Laude, DA, Appling, DR (1996) 13C NMR analysis of the use of alternative donors to the tetrahydrofolate-dependent one-carbon pools in Saccharomyces cerevisiaeArch. Biochem. Biophys. 326(1): 158-165.