I study long-term climate related impacts to human and natural systems that are frequently associated with changes in hydrometeorological extremes. Many urban regions are particularly vulnerable to changing extremes in a number of key areas including: design and construction of buildings, structures, airfields, and roads; flood mitigation and storm water management; water supply and water treatment infrastructure; ecosystem and species management; land, air and water transportation systems; public safety and emergency management procedures. Thus, the quantitative assessment of non-stationary hydrometeorological extremes in a changing climate is important in the context of providing inputs for long-term planning, design standards for infrastructure, and support for management and day-to-day operations.