{"id":18,"date":"2011-11-04T18:07:16","date_gmt":"2011-11-04T18:07:16","guid":{"rendered":"http:\/\/blogs.nd.edu\/championlab\/?page_id=18"},"modified":"2017-03-01T17:41:05","modified_gmt":"2017-03-01T17:41:05","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.nd.edu\/championlab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

\n

Williams EA, Mba Medie F, Bosserman RE, Johnson BK, Reyna C, Ferrell MJ, Champion MM, Abramovitch RB, Champion PA.A Nonsense Mutation in Mycobacterium marinum That Is Suppressible by a Novel Mechanism. Infect Immun<\/em>. 2017 Jan 26;85(2). pii: e00653-16. doi: 10.1128\/IAI.00653-16.<\/p>\n

\nReyna C, Mba Medie F, Champion MM, Champion PA.Rational engineering of a virulence gene from Mycobacterium tuberculosis facilitates proteomic analysis of a natural protein N-terminus. Sci Rep.<\/em> 2016 Sep 14;6:33265. doi: 10.1038\/srep33265.<\/p>\n

Johnson BK, Colvin CJ, Needle DB, Mba Medie F, Champion PA, Abramovitch RB.\u00a0The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits the Mycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence.
\nAntimicrob Agents Chemother.<\/em> 2015 Aug;59(8):4436-45. doi: 10.1128\/AAC.00719-15.<\/p>\n

Zhao Y, Riley NM, Sun L, Hebert AS, Yan X, Westphall MS, Rush MJ, Zhu G, Champion MM, Mba Medie F, Champion PA, Coon JJ, Dovichi NJ.\u00a0Coupling capillary zone electrophoresis with electron transfer dissociation and activated ion electron transfer dissociation for top-down proteomics. Anal Chem<\/em>. 2015;87(10):5422-9. doi: 10.1021\/acs.analchem.5b00883.<\/p>\n

Mba Medie, F., Champion, M.M., Williams, E.A., and\u00a0DiGiuseppe Champion, P.A.\u00a0<\/strong>(2014). Homeostasis of N-a terminal acetylation of EsxA correlates with virulence in\u00a0M. marinum. Infect. Immun.\u00a0<\/em>doi: 10.1128\/IAI.02153-14. Published ahead of print 18 August 2014.<\/p>\n

Champion, M.M, Williams, E.A., Pinapati, R.S. and P.A. DiGiuseppe Champion\u00a0<\/strong>(2014). Correlation of Phenotypic Profiles Using Targeted Proteomics Identifies Mycobacterial Esx-1 Substrates.\u00a0J. Proteome Res.\u00a0<\/em>doi: 10.1021\/pr500484w. Published 8 August 2014.<\/p>\n

Kennedy, G.M, Hooley, G.H., Champion M.M., Mba Medie, F.M. and P.A.\u00a0DiGiuseppe Champion.\u00a0(2014). A novel ESX-1 locus reveals that surface associated ESX-1 substrates mediate virulence in\u00a0Mycobacterium marinum<\/em>\u00a0J. Bacteriol.<\/em>May;196(10):1877-88. doi: 10.1128\/JB.01502-14.<\/em>\u00a0Published ahead of print\u00a07 March 2014.<\/p>\n

Champion PA.\u00a0Disconnecting in vitro ESX-1 secretion from mycobacterial virulence.\u00a0J Bacteriol.<\/em> 2013 Dec;195(24):5418-20.<\/p>\n

Champion, M.M., Williams, E.A., Kennedy, G.M and P.A. DiGiuseppe Champion. (2012) <\/b>Direct Detection of Bacterial Protein Secretion Using Whole Colony Proteomics. Molecular and Cellular Proteomics<\/i>, Sept ;12 (9): 596-604<\/p>\n

Kennedy, G. M., Morisaki, J.K. and P.A. DiGiuseppe Champion. (2012) Conserved mechanisms of Mycobacterium marinum<\/em> pathogenesis within the environmental amoeba, Acanthamoeba castellanii<\/em>. Applied and Environmental Microbiology<\/em>, March \u00a0vol. 78\u00a0no. 6\u00a02049-2052<\/p>\n

Li,Y., \u00a0Champion, M.M., Sun, L., DiGiuseppe Champion, P.A., Wojcik, R., and Norman J. Dovichi. (2012) CZE-ESI-MS\/MS as an alternative proteomics platform to UPLC-ESI-MS\/MS for samples of intermediate complexity. Analytical Chemistry.\u00a0Feb 7;84(3):1617-22<\/em><\/p>\n

Shiloh, M.U. and P.A.<\/em> DiGiuseppe Champion. (2010) To catch a killer: What can mycobacterial models teach us about M. tuberculosis? <\/em>Review, Current Opinions in Microbiology<\/em>, Feb;13(1):86-92.<\/p>\n

DiGiuseppe Champion, P.A., Champion, M.M., Manzanillo, P.M. and J.S. Cox. (2009) ESX-1 Secreted Virulence Factors Are Recognized by Multiple Cytosolic AAA ATPases in Pathogenic Mycobacteria. Molecular Microbiology <\/em>Sep;73(5):950-62.<\/p>\n

Abdallah, A.M., Gey van Pittius, N., DiGiuseppe Champion, P.A., Cox, J.S., Luirink, J., Vandenbroucke-Grauls, C.M.J.E., Appelmelk, B.J. and Bitter, W. (2007) Type VII Secretion, Mycobacterium shows the way. Review, Nature Reviews Microbiology, <\/em>5(11):883-91.
\n<\/span><\/p>\n

DiGiuseppe Champion, P.A. and J.S. Cox. (2007) Protein secretion in Mycobacteria. Review, Cellular Microbiology<\/em> 9 (6), 1376\u20131384.<\/p>\n

DiGiuseppe Champion, P.A., S.A. Stanley, M.M. Champion, E.J. Brown, and J.S. Cox. (2006) C-terminal signal sequence promotes virulence factor secretion in Mycobacterium tuberculosis<\/em>. Science <\/em>15 September Vol. 313. no. 5793, pp. 1583 – 1584.<\/p>\n

Lee, Y.M., P.A. DiGiuseppe, T.J. Silhavy, and S.J. Hultgren. (2004) P. Pilus assembly motif necessary for activation of the CpxRA pathway by PapE in Escherichia coli. J. Bacteriol. <\/em>Jul; 186 (13):4326-4337<\/p>\n

DiGiuseppe, P.A. and T.J. Silhavy. (2003) Signal Detection and Target Gene Expression by the CpxRA Two-Component System. J. Bacteriol. <\/em>Apr; 185(8):2432-40.<\/p>\n","protected":false},"excerpt":{"rendered":"

Williams EA, Mba Medie F, Bosserman RE, Johnson BK, Reyna C, Ferrell MJ, Champion MM, Abramovitch RB, Champion PA.A Nonsense Mutation in Mycobacterium marinum That Is Suppressible by a Novel Mechanism. Infect Immun. 2017 Jan 26;85(2). pii: e00653-16. doi: 10.1128\/IAI.00653-16. … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":471,"featured_media":196,"parent":0,"menu_order":10,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-18","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/sites.nd.edu\/championlab\/wp-json\/wp\/v2\/pages\/18","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.nd.edu\/championlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.nd.edu\/championlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.nd.edu\/championlab\/wp-json\/wp\/v2\/users\/471"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.nd.edu\/championlab\/wp-json\/wp\/v2\/comments?post=18"}],"version-history":[{"count":19,"href":"https:\/\/sites.nd.edu\/championlab\/wp-json\/wp\/v2\/pages\/18\/revisions"}],"predecessor-version":[{"id":207,"href":"https:\/\/sites.nd.edu\/championlab\/wp-json\/wp\/v2\/pages\/18\/revisions\/207"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sites.nd.edu\/championlab\/wp-json\/wp\/v2\/media\/196"}],"wp:attachment":[{"href":"https:\/\/sites.nd.edu\/championlab\/wp-json\/wp\/v2\/media?parent=18"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}