The Littlepage Lab
We study how tumors evolve over time within physiological microenvironments (1) in response to treatment and (2) at the metastatic site. Our research is focused on the contributions of the epithelium and surrounding microenvironment/stroma to both cancer progression and normal tissue development, primarily in the mammary gland and breast cancer. We use this research to understand the mechanisms of cancer progression in order to develop relevant cancer biomarkers and therapies to prevent or reverse cancer in patients.
