{"id":168,"date":"2017-09-07T13:15:01","date_gmt":"2017-09-07T17:15:01","guid":{"rendered":"http:\/\/sites.nd.edu\/pdnano\/?page_id=168"},"modified":"2018-08-30T15:51:08","modified_gmt":"2018-08-30T19:51:08","slug":"nanotoxicology","status":"publish","type":"page","link":"https:\/\/sites.nd.edu\/pdnano\/?page_id=168","title":{"rendered":"Nanotoxicology"},"content":{"rendered":"<p>Nanotoxicity assessment is an integral part of designing biomedical probes. <em>In vitro<\/em> toxicity of nanoparticles is assessed using murine (L929) and human cell lines (HUVEC, RAW246.7). <em>In vivo<\/em> toxicity was assessed in zebrafish models, and <em>in vivo<\/em> biodistribution\/blood pool kinetics was assessed in athymic and euthymic mouse models.<\/p>\n<p><strong>Representative Publications<\/strong><\/p>\n<div id=\"attachment_101\" style=\"width: 104px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/dx.doi.org\/10.1039\/C0NR00080A\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-101\" class=\"wp-image-101\" src=\"http:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/tox-4.png\" alt=\"\" width=\"94\" height=\"92\" srcset=\"https:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/tox-4.png 463w, https:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/tox-4-300x294.png 300w\" sizes=\"auto, (max-width: 94px) 100vw, 94px\" \/><\/a><p id=\"caption-attachment-101\" class=\"wp-caption-text\">Nanoparticles cytotoxicity<\/p><\/div>\n<div id=\"attachment_72\" style=\"width: 136px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/dx.doi.org\/10.1021\/tx300021u\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-72\" class=\"wp-image-72\" src=\"http:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/17.gif\" alt=\"\" width=\"126\" height=\"89\" \/><\/a><p id=\"caption-attachment-72\" class=\"wp-caption-text\">Size-dependent toxicity of\u00a0 nanoparticles<\/p><\/div>\n<div id=\"attachment_178\" style=\"width: 123px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/dx.doi.org\/10.1021\/tx400087d\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-178\" class=\"wp-image-178\" src=\"http:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/1.png\" alt=\"\" width=\"113\" height=\"82\" srcset=\"https:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/1.png 1513w, https:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/1-300x217.png 300w, https:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/1-768x555.png 768w, https:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/1-1024x740.png 1024w\" sizes=\"auto, (max-width: 113px) 100vw, 113px\" \/><\/a><p id=\"caption-attachment-178\" class=\"wp-caption-text\">Charge-dependent toxicity of nanoparticles<\/p><\/div>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<div id=\"attachment_73\" style=\"width: 307px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/dx.doi.org\/10.1039\/C4NR06441K\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-73\" class=\"wp-image-73\" src=\"http:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/18.gif\" alt=\"\" width=\"297\" height=\"189\" \/><\/a><p id=\"caption-attachment-73\" class=\"wp-caption-text\">Radiolabeling nanoparticles for biodistribution studies<\/p><\/div>\n<h6><\/h6>\n<h6><\/h6>\n<h6><\/h6>\n<h6><\/h6>\n<h6><\/h6>\n<h6><\/h6>\n<h6><\/h6>\n<h6 style=\"text-align: right\"><a href=\"http:\/\/sites.nd.edu\/pdnano\"><span style=\"text-decoration: underline\">BACK<\/span><\/a><\/h6>\n","protected":false},"excerpt":{"rendered":"<p>Nanotoxicity assessment is an integral part of designing biomedical probes. In vitro toxicity of nanoparticles is assessed using murine (L929) and human cell lines (HUVEC, RAW246.7). In vivo toxicity was assessed in zebrafish models, and in vivo biodistribution\/blood pool kinetics was assessed in athymic and euthymic mouse models. Representative Publications &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &hellip; <\/p>\n<p><a class=\"more-link block-button\" href=\"https:\/\/sites.nd.edu\/pdnano\/?page_id=168\">Continue reading &raquo;<\/a><\/p>\n","protected":false},"author":2671,"featured_media":0,"parent":158,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-168","page","type-page","status-publish","hentry","nodate"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Nanotoxicology - Nallathamby Laboratory<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.nd.edu\/pdnano\/?page_id=168\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nanotoxicology - Nallathamby Laboratory\" \/>\n<meta property=\"og:description\" content=\"Nanotoxicity assessment is an integral part of designing biomedical probes. In vitro toxicity of nanoparticles is assessed using murine (L929) and human cell lines (HUVEC, RAW246.7). In vivo toxicity was assessed in zebrafish models, and in vivo biodistribution\/blood pool kinetics was assessed in athymic and euthymic mouse models. 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In vitro toxicity of nanoparticles is assessed using murine (L929) and human cell lines (HUVEC, RAW246.7). In vivo toxicity was assessed in zebrafish models, and in vivo biodistribution\/blood pool kinetics was assessed in athymic and euthymic mouse models. 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