{"id":171,"date":"2017-09-07T09:04:25","date_gmt":"2017-09-07T13:04:25","guid":{"rendered":"http:\/\/sites.nd.edu\/pdnano\/?page_id=171"},"modified":"2018-08-30T15:39:57","modified_gmt":"2018-08-30T19:39:57","slug":"biomedical-image-contrast-agents","status":"publish","type":"page","link":"https:\/\/sites.nd.edu\/pdnano\/?page_id=171","title":{"rendered":"Biomedical Image Contrast Agents"},"content":{"rendered":"<p class=\"font_8\">Scaled up the synthesis of nanoparticle contrast agents. I specialize in the synthesis of long emission lifetime, fluorescent and photoluminescent nanoparticles. This is achieved by modifying Au cores with fluorophore embedded shells or Au nanoclusters with tunable photoluminescence. Fluorescent silica particles with sizes ranging from 15 nm to 400 nm are also available. Such probes have been applied in tracking single molecules on live cells over the course of 12h and in super-resolution optical imaging.<\/p>\n<ul class=\"font_8\">\n<li>\n<p class=\"font_8\">Dual mode detectable probes include: Fluorescent\/X-ray and Fluorescent\/MRI<\/p>\n<\/li>\n<li>\n<p class=\"font_8\">Triple Mode detectable probes include: Fluorescent\/X-ray\/MRI probes<\/p>\n<\/li>\n<li>\n<p class=\"font_8\">Plasmonic, fluorescence, MRI, X-ray modalities of detection in a mouse animal model. Single mode and multi-mode detections<\/p>\n<\/li>\n<\/ul>\n<p><strong>Representative Publications<\/strong><\/p>\n<div id=\"attachment_80\" style=\"width: 158px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/dx.doi.org\/10.1039\/C6TB01659F\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-80\" class=\"wp-image-80\" src=\"http:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/25-e1504642498147.gif\" alt=\"\" width=\"148\" height=\"74\" \/><\/a><p id=\"caption-attachment-80\" class=\"wp-caption-text\">Targeted X-ray contrast and fluorescent core-shell nanoparticles<\/p><\/div>\n<div id=\"attachment_741\" style=\"width: 114px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-741\" class=\"wp-image-741\" src=\"http:\/\/sites.nd.edu\/pdnano\/files\/2018\/08\/Picture2-300x253.png\" alt=\"http:\/\/dx.doi.org\/10.1117\/12.2255688\" width=\"104\" height=\"87\" srcset=\"https:\/\/sites.nd.edu\/pdnano\/files\/2018\/08\/Picture2-300x253.png 300w, https:\/\/sites.nd.edu\/pdnano\/files\/2018\/08\/Picture2-768x648.png 768w, https:\/\/sites.nd.edu\/pdnano\/files\/2018\/08\/Picture2-1024x864.png 1024w, https:\/\/sites.nd.edu\/pdnano\/files\/2018\/08\/Picture2.png 1143w\" sizes=\"auto, (max-width: 104px) 100vw, 104px\" \/><p id=\"caption-attachment-741\" class=\"wp-caption-text\">Spectral CT Probes<\/p><\/div>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h6><\/h6>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h6 style=\"text-align: right\"><a href=\"http:\/\/sites.nd.edu\/pdnano\"><span style=\"text-decoration: underline\">BACK<\/span><\/a><\/h6>\n","protected":false},"excerpt":{"rendered":"<p>Scaled up the synthesis of nanoparticle contrast agents. I specialize in the synthesis of long emission lifetime, fluorescent and photoluminescent nanoparticles. This is achieved by modifying Au cores with fluorophore embedded shells or Au nanoclusters with tunable photoluminescence. Fluorescent silica particles with sizes ranging from 15 nm to 400 nm are also available. Such probes &hellip; <\/p>\n<p><a class=\"more-link block-button\" href=\"https:\/\/sites.nd.edu\/pdnano\/?page_id=171\">Continue reading &raquo;<\/a><\/p>\n","protected":false},"author":2671,"featured_media":0,"parent":158,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-171","page","type-page","status-publish","hentry","nodate"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Biomedical Image Contrast Agents - Nallathamby Laboratory<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.nd.edu\/pdnano\/?page_id=171\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Biomedical Image Contrast Agents - Nallathamby Laboratory\" \/>\n<meta property=\"og:description\" content=\"Scaled up the synthesis of nanoparticle contrast agents. I specialize in the synthesis of long emission lifetime, fluorescent and photoluminescent nanoparticles. This is achieved by modifying Au cores with fluorophore embedded shells or Au nanoclusters with tunable photoluminescence. Fluorescent silica particles with sizes ranging from 15 nm to 400 nm are also available. Such probes &hellip; Continue reading &raquo;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sites.nd.edu\/pdnano\/?page_id=171\" \/>\n<meta property=\"og:site_name\" content=\"Nallathamby Laboratory\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/prakashdn\" \/>\n<meta property=\"article:modified_time\" content=\"2018-08-30T19:39:57+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/25-e1504642498147.gif\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@prakashdn\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?page_id=171\",\"url\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?page_id=171\",\"name\":\"Biomedical Image Contrast Agents - Nallathamby Laboratory\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?page_id=171#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?page_id=171#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/sites.nd.edu\\\/pdnano\\\/files\\\/2017\\\/09\\\/25-e1504642498147.gif\",\"datePublished\":\"2017-09-07T13:04:25+00:00\",\"dateModified\":\"2018-08-30T19:39:57+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?page_id=171#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?page_id=171\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?page_id=171#primaryimage\",\"url\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/files\\\/2017\\\/09\\\/25-e1504642498147.gif\",\"contentUrl\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/files\\\/2017\\\/09\\\/25-e1504642498147.gif\",\"width\":150,\"height\":75},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?page_id=171#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research Focus Areas\",\"item\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Biomedical Image Contrast Agents\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/#website\",\"url\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/\",\"name\":\"Modular Nanotechnologies and Nanomaterials\",\"description\":\"Modular and scalable nanotechnology for imaging, sensing and therapeutics\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Biomedical Image Contrast Agents - Nallathamby Laboratory","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/sites.nd.edu\/pdnano\/?page_id=171","og_locale":"en_US","og_type":"article","og_title":"Biomedical Image Contrast Agents - Nallathamby Laboratory","og_description":"Scaled up the synthesis of nanoparticle contrast agents. I specialize in the synthesis of long emission lifetime, fluorescent and photoluminescent nanoparticles. This is achieved by modifying Au cores with fluorophore embedded shells or Au nanoclusters with tunable photoluminescence. Fluorescent silica particles with sizes ranging from 15 nm to 400 nm are also available. Such probes &hellip; Continue reading &raquo;","og_url":"https:\/\/sites.nd.edu\/pdnano\/?page_id=171","og_site_name":"Nallathamby Laboratory","article_publisher":"https:\/\/www.facebook.com\/prakashdn","article_modified_time":"2018-08-30T19:39:57+00:00","og_image":[{"url":"http:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/25-e1504642498147.gif","type":"","width":"","height":""}],"twitter_card":"summary_large_image","twitter_site":"@prakashdn","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/sites.nd.edu\/pdnano\/?page_id=171","url":"https:\/\/sites.nd.edu\/pdnano\/?page_id=171","name":"Biomedical Image Contrast Agents - Nallathamby Laboratory","isPartOf":{"@id":"https:\/\/sites.nd.edu\/pdnano\/#website"},"primaryImageOfPage":{"@id":"https:\/\/sites.nd.edu\/pdnano\/?page_id=171#primaryimage"},"image":{"@id":"https:\/\/sites.nd.edu\/pdnano\/?page_id=171#primaryimage"},"thumbnailUrl":"http:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/25-e1504642498147.gif","datePublished":"2017-09-07T13:04:25+00:00","dateModified":"2018-08-30T19:39:57+00:00","breadcrumb":{"@id":"https:\/\/sites.nd.edu\/pdnano\/?page_id=171#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/sites.nd.edu\/pdnano\/?page_id=171"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/sites.nd.edu\/pdnano\/?page_id=171#primaryimage","url":"https:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/25-e1504642498147.gif","contentUrl":"https:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/25-e1504642498147.gif","width":150,"height":75},{"@type":"BreadcrumbList","@id":"https:\/\/sites.nd.edu\/pdnano\/?page_id=171#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/sites.nd.edu\/pdnano\/"},{"@type":"ListItem","position":2,"name":"Research Focus Areas","item":"https:\/\/sites.nd.edu\/pdnano\/"},{"@type":"ListItem","position":3,"name":"Biomedical Image Contrast Agents"}]},{"@type":"WebSite","@id":"https:\/\/sites.nd.edu\/pdnano\/#website","url":"https:\/\/sites.nd.edu\/pdnano\/","name":"Modular Nanotechnologies and Nanomaterials","description":"Modular and scalable nanotechnology for imaging, sensing and therapeutics","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/sites.nd.edu\/pdnano\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=\/wp\/v2\/pages\/171","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=\/wp\/v2\/users\/2671"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=171"}],"version-history":[{"count":15,"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=\/wp\/v2\/pages\/171\/revisions"}],"predecessor-version":[{"id":1316,"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=\/wp\/v2\/pages\/171\/revisions\/1316"}],"up":[{"embeddable":true,"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=\/wp\/v2\/pages\/158"}],"wp:attachment":[{"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=171"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}