{"id":131,"date":"2017-09-03T12:27:34","date_gmt":"2017-09-03T16:27:34","guid":{"rendered":"http:\/\/sites.nd.edu\/pdnano\/?p=131"},"modified":"2024-01-11T11:46:06","modified_gmt":"2024-01-11T15:46:06","slug":"131","status":"publish","type":"post","link":"https:\/\/sites.nd.edu\/pdnano\/?p=131","title":{"rendered":"Non-Sintered Metal Oxide Nanocrystals"},"content":{"rendered":"
\"\"

Well dispersed Gadolinium oxide nanoparticles and nanoplates were synthesized. A silica shell was used to increase biocompatibility.<\/p><\/div>\n

Nanoparticles (NPs) due to their size scale being 1-100 nm, are characterized by a greater surface area per unit mass than the bulk phase of the same material, which makes NPs display chemical reactivity and physical properties that approach the atomic phase.<\/p>\n

NPs derived from lanthanides (e.g. gadolinium, europium, etc.) \u00a0in particular attract a lot of attention because of their unusual optical, magnetic, electrical, and catalytic properties. For instance, gadolinium oxideNPs are used as positive contrast agent in T1 weighted MRI scans due to the unique magnetic properties of gadolinium.<\/p>\n

At present, commonly employed approaches for the synthesis of gadolinia\u00a0NPs involve thermal decomposition techniques or metal co-precipitation protocols. While these methods yield nanocrystal units in the order of 5-20 nm, the actual hydrodynamic radius is a 100 fold higher (500-1000 nm). The high hydrodynamic radius\u00a0causes colloidal agglomeration\u00a0in solution. This\u00a0makes these NPs highly unsuitable for in vivo biomedical applications or incorporation into 3D printing inks.<\/p>\n

Our ongoing research has tackled this problem of super-agglomeration of metal oxides in solution by\u00a0synthesizing\u00a0non-sintered, well separated, water dispersed nanocrystals of metal oxides (iron oxde, gadolinium oxide and hafnium oxides). Our synthesis technique has broad applications in\u00a0creating metal pigment inks for additive manufacturing. \u00a0Additionally, we possess the ability to incorporate these metal oxide cores in biocompatible shells such as silica to make them suitable for in vivo applications.<\/p>\n

Our paper detailing this synthetic technique will be published this\u00a0Fall, 2017<\/p>\n","protected":false},"excerpt":{"rendered":"

Nanoparticles (NPs) due to their size scale being 1-100 nm, are characterized by a greater surface area per unit mass than the bulk phase of the same material, which makes NPs display chemical reactivity and physical properties that approach the atomic phase. NPs derived from lanthanides (e.g. gadolinium, europium, etc.) \u00a0in particular attract a lot … <\/p>\n

Continue reading »<\/a><\/p>\n","protected":false},"author":2672,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[405093,259656,259762,259341],"tags":[],"class_list":["post-131","post","type-post","status-publish","format-standard","hentry","category-berthiaume-institute-for-precision-health","category-biomedical-imaging","category-mri","category-upcoming-manuscripts"],"yoast_head":"\nNon-Sintered Metal Oxide Nanocrystals - Nallathamby Laboratory<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.nd.edu\/pdnano\/?p=131\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Non-Sintered Metal Oxide Nanocrystals - Nallathamby Laboratory\" \/>\n<meta property=\"og:description\" content=\"Nanoparticles (NPs) due to their size scale being 1-100 nm, are characterized by a greater surface area per unit mass than the bulk phase of the same material, which makes NPs display chemical reactivity and physical properties that approach the atomic phase. NPs derived from lanthanides (e.g. gadolinium, europium, etc.) \u00a0in particular attract a lot … Continue reading »\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sites.nd.edu\/pdnano\/?p=131\" \/>\n<meta property=\"og:site_name\" content=\"Nallathamby Laboratory\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/prakashdn\" \/>\n<meta property=\"article:published_time\" content=\"2017-09-03T16:27:34+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-01-11T15:46:06+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/cropped-tool-box-2-300x63.png\" \/>\n<meta name=\"author\" content=\"Prakash\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@prakashdn\" \/>\n<meta name=\"twitter:site\" content=\"@prakashdn\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Prakash\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?p=131#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?p=131\"},\"author\":{\"name\":\"Prakash\",\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/#\\\/schema\\\/person\\\/3bec2d9fbd957b23abd53a0a5445b4f0\"},\"headline\":\"Non-Sintered Metal Oxide Nanocrystals\",\"datePublished\":\"2017-09-03T16:27:34+00:00\",\"dateModified\":\"2024-01-11T15:46:06+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?p=131\"},\"wordCount\":270,\"image\":{\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?p=131#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/sites.nd.edu\\\/pdnano\\\/files\\\/2017\\\/09\\\/cropped-tool-box-2-300x63.png\",\"articleSection\":[\"Berthiaume Institute for Precision Health\",\"Biomedical Imaging\",\"MRI\",\"Upcoming manuscripts\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?p=131\",\"url\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?p=131\",\"name\":\"Non-Sintered Metal Oxide Nanocrystals - Nallathamby Laboratory\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?p=131#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?p=131#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/sites.nd.edu\\\/pdnano\\\/files\\\/2017\\\/09\\\/cropped-tool-box-2-300x63.png\",\"datePublished\":\"2017-09-03T16:27:34+00:00\",\"dateModified\":\"2024-01-11T15:46:06+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/#\\\/schema\\\/person\\\/3bec2d9fbd957b23abd53a0a5445b4f0\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?p=131#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?p=131\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?p=131#primaryimage\",\"url\":\"http:\\\/\\\/sites.nd.edu\\\/pdnano\\\/files\\\/2017\\\/09\\\/cropped-tool-box-2-300x63.png\",\"contentUrl\":\"http:\\\/\\\/sites.nd.edu\\\/pdnano\\\/files\\\/2017\\\/09\\\/cropped-tool-box-2-300x63.png\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?p=131#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Non-Sintered Metal Oxide Nanocrystals\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/#website\",\"url\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/\",\"name\":\"Modular Nanotechnologies and Nanomaterials\",\"description\":\"Modular and scalable nanotechnology for imaging, sensing and therapeutics\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/#\\\/schema\\\/person\\\/3bec2d9fbd957b23abd53a0a5445b4f0\",\"name\":\"Prakash\",\"url\":\"https:\\\/\\\/sites.nd.edu\\\/pdnano\\\/?author=2672\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Non-Sintered Metal Oxide Nanocrystals - Nallathamby Laboratory","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/sites.nd.edu\/pdnano\/?p=131","og_locale":"en_US","og_type":"article","og_title":"Non-Sintered Metal Oxide Nanocrystals - Nallathamby Laboratory","og_description":"Nanoparticles (NPs) due to their size scale being 1-100 nm, are characterized by a greater surface area per unit mass than the bulk phase of the same material, which makes NPs display chemical reactivity and physical properties that approach the atomic phase. NPs derived from lanthanides (e.g. gadolinium, europium, etc.) \u00a0in particular attract a lot … Continue reading »","og_url":"https:\/\/sites.nd.edu\/pdnano\/?p=131","og_site_name":"Nallathamby Laboratory","article_publisher":"https:\/\/www.facebook.com\/prakashdn","article_published_time":"2017-09-03T16:27:34+00:00","article_modified_time":"2024-01-11T15:46:06+00:00","og_image":[{"url":"http:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/cropped-tool-box-2-300x63.png","type":"","width":"","height":""}],"author":"Prakash","twitter_card":"summary_large_image","twitter_creator":"@prakashdn","twitter_site":"@prakashdn","twitter_misc":{"Written by":"Prakash","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/sites.nd.edu\/pdnano\/?p=131#article","isPartOf":{"@id":"https:\/\/sites.nd.edu\/pdnano\/?p=131"},"author":{"name":"Prakash","@id":"https:\/\/sites.nd.edu\/pdnano\/#\/schema\/person\/3bec2d9fbd957b23abd53a0a5445b4f0"},"headline":"Non-Sintered Metal Oxide Nanocrystals","datePublished":"2017-09-03T16:27:34+00:00","dateModified":"2024-01-11T15:46:06+00:00","mainEntityOfPage":{"@id":"https:\/\/sites.nd.edu\/pdnano\/?p=131"},"wordCount":270,"image":{"@id":"https:\/\/sites.nd.edu\/pdnano\/?p=131#primaryimage"},"thumbnailUrl":"http:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/cropped-tool-box-2-300x63.png","articleSection":["Berthiaume Institute for Precision Health","Biomedical Imaging","MRI","Upcoming manuscripts"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/sites.nd.edu\/pdnano\/?p=131","url":"https:\/\/sites.nd.edu\/pdnano\/?p=131","name":"Non-Sintered Metal Oxide Nanocrystals - Nallathamby Laboratory","isPartOf":{"@id":"https:\/\/sites.nd.edu\/pdnano\/#website"},"primaryImageOfPage":{"@id":"https:\/\/sites.nd.edu\/pdnano\/?p=131#primaryimage"},"image":{"@id":"https:\/\/sites.nd.edu\/pdnano\/?p=131#primaryimage"},"thumbnailUrl":"http:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/cropped-tool-box-2-300x63.png","datePublished":"2017-09-03T16:27:34+00:00","dateModified":"2024-01-11T15:46:06+00:00","author":{"@id":"https:\/\/sites.nd.edu\/pdnano\/#\/schema\/person\/3bec2d9fbd957b23abd53a0a5445b4f0"},"breadcrumb":{"@id":"https:\/\/sites.nd.edu\/pdnano\/?p=131#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/sites.nd.edu\/pdnano\/?p=131"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/sites.nd.edu\/pdnano\/?p=131#primaryimage","url":"http:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/cropped-tool-box-2-300x63.png","contentUrl":"http:\/\/sites.nd.edu\/pdnano\/files\/2017\/09\/cropped-tool-box-2-300x63.png"},{"@type":"BreadcrumbList","@id":"https:\/\/sites.nd.edu\/pdnano\/?p=131#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/sites.nd.edu\/pdnano\/"},{"@type":"ListItem","position":2,"name":"Non-Sintered Metal Oxide Nanocrystals"}]},{"@type":"WebSite","@id":"https:\/\/sites.nd.edu\/pdnano\/#website","url":"https:\/\/sites.nd.edu\/pdnano\/","name":"Modular Nanotechnologies and Nanomaterials","description":"Modular and scalable nanotechnology for imaging, sensing and therapeutics","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/sites.nd.edu\/pdnano\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/sites.nd.edu\/pdnano\/#\/schema\/person\/3bec2d9fbd957b23abd53a0a5445b4f0","name":"Prakash","url":"https:\/\/sites.nd.edu\/pdnano\/?author=2672"}]}},"_links":{"self":[{"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=\/wp\/v2\/posts\/131","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=\/wp\/v2\/users\/2672"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=131"}],"version-history":[{"count":6,"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=\/wp\/v2\/posts\/131\/revisions"}],"predecessor-version":[{"id":251,"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=\/wp\/v2\/posts\/131\/revisions\/251"}],"wp:attachment":[{"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=131"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=131"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.nd.edu\/pdnano\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=131"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}