{"id":1854,"date":"2025-05-22T09:50:22","date_gmt":"2025-05-22T13:50:22","guid":{"rendered":"https:\/\/sites.nd.edu\/pdnano\/?p=1854"},"modified":"2025-12-09T03:34:53","modified_gmt":"2025-12-09T07:34:53","slug":"lab-secures-cdmrp-funding-to-supercharge-car-t-therapy","status":"publish","type":"post","link":"https:\/\/sites.nd.edu\/pdnano\/?p=1854","title":{"rendered":"Lab Secures CDMRP PRCRP Funding to Supercharge CAR-T Therapy"},"content":{"rendered":"
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I am pleased to announce that our lab has been awarded a new grant from the Congressionally Directed Medical Research Programs (CDMRP) – Peer Reviewed Cancer Research Program (PRCRP)<\/strong>.<\/p>\n\n\n\n

Running from 2025 to 2027, this project (Award No. HT94252510332) is titled “Multispecific Bridge Nanoparticles to Engage T Cells and Off-the-Shelf CAR-T Cells Against Antigen(+) EC Tumors to Enhance Antitumor Immune Activity.”<\/strong><\/p>\n\n\n\n

This funding will support our research into “bridge nanoparticles”\u2014a novel platform designed to physically link T cells and off-the-shelf CAR-T cells directly to tumors. By creating a stronger engagement between the immune system and the cancer cells, we aim to significantly enhance antitumor immune activity and improve outcomes for patients with antigen-positive EC tumors.<\/p>\n\n\n\n

We are grateful for the support from the CDMRP and look forward to advancing this promising technology over the next two years. All glory be to Jesus for this timely award.<\/p>\n\n\n\n

https:\/\/precisionhealth.nd.edu\/news-events\/news\/notre-dame-researchers-pioneer-the-use-of-bridge-nanoparticles-to-fight-esophageal-cancer<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

I am pleased to announce that our lab has been awarded a new grant from the Congressionally Directed Medical Research Programs (CDMRP) – Peer Reviewed Cancer Research Program (PRCRP). Running from 2025 to 2027, this project (Award No. HT94252510332) is titled “Multispecific Bridge Nanoparticles to Engage T Cells and Off-the-Shelf CAR-T Cells Against Antigen(+) EC … <\/p>\n

Continue reading »<\/a><\/p>\n","protected":false},"author":2672,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1854","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"\nLab Secures CDMRP PRCRP Funding to Supercharge CAR-T Therapy - Nallathamby Laboratory<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.nd.edu\/pdnano\/?p=1854\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lab Secures CDMRP PRCRP Funding to Supercharge CAR-T Therapy - Nallathamby Laboratory\" \/>\n<meta property=\"og:description\" content=\"I am pleased to announce that our lab has been awarded a new grant from the Congressionally Directed Medical Research Programs (CDMRP) – Peer Reviewed Cancer Research Program (PRCRP). 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