{"id":77,"date":"2021-02-09T15:43:55","date_gmt":"2021-02-09T20:43:55","guid":{"rendered":"https:\/\/sites.nd.edu\/santiago-tirado-lab\/?page_id=77"},"modified":"2022-11-18T12:20:31","modified_gmt":"2022-11-18T17:20:31","slug":"welcome-to-the-santiago-tirado-lab","status":"publish","type":"page","link":"https:\/\/sites.nd.edu\/santiago-tirado-lab\/","title":{"rendered":"Welcome to the Santiago-Tirado Lab"},"content":{"rendered":"<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"307\" src=\"https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/02\/Banner_Crypto-cryo-EM-1024x307.jpg\" alt=\"\" class=\"wp-image-85\" srcset=\"https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/02\/Banner_Crypto-cryo-EM-1024x307.jpg 1024w, https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/02\/Banner_Crypto-cryo-EM-300x90.jpg 300w, https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/02\/Banner_Crypto-cryo-EM-768x230.jpg 768w, https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/02\/Banner_Crypto-cryo-EM-1536x460.jpg 1536w, https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/02\/Banner_Crypto-cryo-EM-2048x613.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Here we are excited by the cell biology of the environmental fungus <em>Cryptococcus neoformans<\/em>, and by the fascinating cellular interactions this yeast exhibits with its host cells. The Santiago-Tirado Lab combines its expertise in cell biology with training in fungal pathogenesis, and we aim to understand how <em>C. neoformans<\/em> can survive inside host phagocytes and cross cellular barriers, which are the main drivers of disease progression. We are also interested in the unique cell biology of this fungus, especially on the function of its many virulence factors, offering the potential to uncover novel therapeutic targets as well as insights applicable to other fungal or respiratory pathogens.<\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"314\" src=\"https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/03\/Cpl1-mCherry_crop.jpg\" alt=\"\" class=\"wp-image-215\" srcset=\"https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/03\/Cpl1-mCherry_crop.jpg 400w, https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/03\/Cpl1-mCherry_crop-300x236.jpg 300w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"314\" src=\"https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/03\/pfa_crop.jpg\" alt=\"\" class=\"wp-image-248\" srcset=\"https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/03\/pfa_crop.jpg 400w, https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/03\/pfa_crop-300x236.jpg 300w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/figure>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"314\" src=\"https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/03\/Max_crop.jpg\" alt=\"\" class=\"wp-image-247\" srcset=\"https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/03\/Max_crop.jpg 400w, https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/03\/Max_crop-300x236.jpg 300w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"300\" src=\"https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/03\/pfa4_2_Indiainl.jpg\" alt=\"\" class=\"wp-image-217\" srcset=\"https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/03\/pfa4_2_Indiainl.jpg 400w, https:\/\/sites.nd.edu\/santiago-tirado-lab\/files\/2021\/03\/pfa4_2_Indiainl-300x225.jpg 300w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/figure>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Here we are excited by the cell biology of the environmental fungus Cryptococcus neoformans, and by the fascinating cellular interactions this yeast exhibits with its host cells. The Santiago-Tirado Lab combines its expertise in cell biology with training in fungal pathogenesis, and we aim to understand how C. neoformans can survive inside host phagocytes and [&hellip;]<\/p>\n","protected":false},"author":3893,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-77","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.nd.edu\/santiago-tirado-lab\/wp-json\/wp\/v2\/pages\/77","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.nd.edu\/santiago-tirado-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.nd.edu\/santiago-tirado-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.nd.edu\/santiago-tirado-lab\/wp-json\/wp\/v2\/users\/3893"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.nd.edu\/santiago-tirado-lab\/wp-json\/wp\/v2\/comments?post=77"}],"version-history":[{"count":33,"href":"https:\/\/sites.nd.edu\/santiago-tirado-lab\/wp-json\/wp\/v2\/pages\/77\/revisions"}],"predecessor-version":[{"id":381,"href":"https:\/\/sites.nd.edu\/santiago-tirado-lab\/wp-json\/wp\/v2\/pages\/77\/revisions\/381"}],"wp:attachment":[{"href":"https:\/\/sites.nd.edu\/santiago-tirado-lab\/wp-json\/wp\/v2\/media?parent=77"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}