Technical Program
All meeting events will occur in Room 105 and the Galleria of the Jordan Hall of Science, University of Notre Dame.
A PDF copy of the technical program can be accessed here MCGS Technical Program. Printed copies of the technical program will be distributed at the symposium.
The draft for the meal plan can be accessed here MCGS_Meal_Plan_DRAFT.
Schedule of Events
Friday, September 20, 2019
4:30 – 6:15 pm
Meeting Registration; Poster Setup
Jordan Hall of Science – Galleria
Session I
Jordan Hall of Science – Room 105
Chair: Linda Hsieh-Wilson (CalTech)
6:25 – 6:30 pm
Introductory Remarks
Anthony S. Serianni
6:30 – 7:00 pm
Dr. Richard D. Cummings
Professor, Department of Surgery, Harvard University
Recognizing Sugars – Chemical Biology and Physiological Roles
7:00 – 7:15 pm
Nicholas Banahene
Student, Swarts Lab, Department of Chemistry and Biochemistry, Central Michigan University
O-Acylated Trehalose Analogues for Probing Cellular Processes and Components in Corynebacterineae
7:15 – 7:45 pm
Dr. Joseph J. Barchi Jr.
Senior Scientist, Center for Cancer Research, National Cancer Institute
The Thomsen Friedenreich Tumor-Associated Carbohydrate Antigen in Anticancer Drug Discovery
7:45 – 8:15 pm
Break; Poster Session
Jordan Hall of Science – Galleria
8:15 – 8:30 pm
Shuyao Lang
Student, Huang Lab, Department of Chemistry and Biomedical Engineering, Michigan State University
Glyco-engineering of Natural Killers Cells with CD22 Ligands for Effective Anti-Cancer Immunotherapy
8:30 – 9:00 pm
Dr. Roger A. Laine
Department of Biological Sciences, Department of Chemistry, Louisiana State University
Chief Executive Officer, TumorEnd, LLC.
Polysaccharides as Tumor Therapeutics, 1868-2019
9:00 pm
Reception; Poster Session
Jordan Hall of Science – Galleria
Saturday, September 21, 2019
7:30 – 8:15 am
Continental Breakfast (Jordan Hall)
Jordan Hall of Science – Galleria
Session II
Jordan Hall of Science – Room 105
Chair: Peter Andreana (University of Toledo)
8:15 – 8:30 am
Dr. Mary Prorok
Assistant Chair, Department of Chemistry and Biochemistry, University of Notre Dame
The Evolution of Laboratory Safety at Notre Dame
8:30 – 9:00 am
Dr. Linda Hsieh-Wilson
Professor, Division of Chemistry and Chemical Engineering, California Institute of Technology
Streamlined Methods for the Synthesis and Study of Heparin Sulfate Oligosaccharides
9:00 – 9:15 am
Jicheng Zhang
Student, Huang Lab, Department of Chemistry, Michigan State University
Chemical Synthesis of Heparin Like Head to Tail Multimers
9:15 – 9:45 am
Dr. Norman J. Dovichi
Professor, Department of Chemistry and Biochemistry, University of Notre Dame
Capillary Electrophoresis-Mass Spectrometry Reveals the N-Glycome During Vertebrate Embryogenesis
9:45 – 10:45 am
Break; Poster Session
Jordan Hall of Science – Galleria
10:45 – 11:00 am
Mithila D. Bandara
Student, Demchenko Lab, Department of Chemistry and Biochemistry, University of Missouri-St. Louis
Synthesis of Human Milk Oligosaccharides
11:00 – 11:30 am
Dr. Jacquelyn Gervay-Hague
Professor, Department of Chemistry, University of California, Davis
Protecting Group Modulation of Glycosyl Iodide Reactivity to Yield Metabolic Probes of Interspecies Chemical Communication
11:30 – 11:45 am
Sonia Tomar
Student, Sun Lab, Department of Chemistry, Cleveland State University
Investigation of Substrate Specificity of Sialidases with Membrane Mimetic Glycoconjugates
11:45 am – 1:45 pm
Lunch; Poster Session
Jordan Hall of Science – Galleria
1:00 – 1:45 pm
PI Meeting
Jordan Hall of Science – Reading Room
Session III
Jordan Hall of Science – Room 105
Chair: Jacquelyn Gervay-Hague (UC-Davis)
1:45 – 2:15 pm
Dr. Shahriar Mobashery
Professor, Department of Chemistry and Biochemistry, University of Notre Dame
Cell-Wall Recycling in Pseudomonas aeruginosa and the Nexus to Antibiotic Resistance
2:15 – 2:30 pm
Jia Gao
Student, Huang Lab, Department of Chemistry, Michigan State University
Chemoenzymatic Synthesis of Heparan Sulfate Glycopeptide Mimetics and Evaluation of Its Biological Functions
2:30 – 3:00 pm
Dr. Ming Tien
Professor, Department of Biochemistry and Molecular Biology, The Pennsylvania State University
Initiation, Elongation and Termination of Bacterial Cellulose Synthesis
3:00 – 3:30 pm
Break; Poster Session
Jordan Hall of Science – Galleria
3:30 – 3:45 pm
Dr. Jiaoyang Jiang
Associate Professor, Pharmaceutical Sciences Division, University of Wisconsin-Madison
Targeted Covalent Inhibition of O-GlcNAc Transferase in Cells
3:45 – 4:15 pm
Dr. Darón I. Freedberg
Research Chemist, U.S. Food & Drug Administration
Hydrogen Bonding in the Conformations of Glycans
4:15 – 4:30 pm
Matteo Panza
Student, Demchenko Lab, Department of Chemistry and Biochemistry, University of Missouri-St. Louis
HPLC-Based Oligosaccharide Synthesis: Entirely Automated Glycan Synthesis
4:30 – 5:00 pm
Dr. Robert J. Woods
Professor, Department of Biochemistry and Molecular Biology, Department of Chemistry, Complex Carbohydrate Research Center, University of Georgia
Glycomimetics to Inhibit Influenza Infection
5:00 – 5:30 pm
Awards; Concluding Remarks
5:30 – 6:15 pm
Poster Breakdown
6:15 pm
Dinner
Jordan Hall of Science – Galleria
List of Posters
| 1 | Catherine Alex | Hydrogen-Bond-Mediated Aglycone Delivery for Stereocontrolled β-Mannosylation |
| 2 | Aathmaja Anandhi Rangarajan | Characterizing Spacial and Metabolic Relationships between the Gut Microbes Bacteriodes thetaiotaomicron and Ruminococcus bromii during Resistant Startch Degradation |
| 3 | Luis Avila | Elucidating the Interactome of the Lytic Transglycosylase RlpA of Pseudomonas aeruginosa |
| 4 | Kedar Baryal | Synthesis of a Comprehensive Heparan Sulfate Tetrasaccharide Library |
| 5 | Bishwa Bhetuwal | Cs2CO3-Mediated Anomeric O-Alkylation: Stereoselective Synthesis of β-Mannosamines and Synthesis of Representative Bacterial Capsular Polysaccharides |
| 6 | Stephanie Blaszczyk | Chiral Benzotetramisole-Catalyzed Site-Selective Acylation of Carbohydrates Directed by Anomeric S-Adamantyl Group |
| 7 | Ka Keung Chan | Synthesis and Evaluation of Chain-End Functionalized N-Glycan Polymers as Biomimetic Macro-Glycoligands |
| 8 | Shivangi Chugh and Zahra Rashidi | Exploring Bacteriophage Qβ Virus-like Particle as a Platform to Design Vaccines for Various Applications |
| 9 | Vinod Kumar Gattoji | Synthesis of Entirely Carbohydrate Immunogen GD2-PS A1 and Production of Anti-GD2 mABs |
| 10 | Laurent Geffroy | Dynamics of Three Carbohydrate Utilization System Glycoside Hydrolases Probed by Single-Molecule Fluorescence Measurements |
| 11 | Dana Gepford | Synthesis of Fluorogenic Trehalose and Trehalose Monomycolate Analogues for the Detection of Mycobacteria |
| 12 | Jessica Groenevelt | Pharmacological Targeting of O-GlcNAc Readers via Glycopeptide Mimetics |
| 13 | Ishani Hettiarachchi | Synthesis of Trisaccharide Oligomer of Salmonella E1 Capsular Polysaccharide via Anomeric O-Alkylation |
| 14 | Joseph Keil | Site-Specific Glyco-Engineering of Recombinant Thrombomodulin |
| 15 | Saniya Shehbaz Khan | Synthesis of Tetrahydrolipstatin Congerners for Inhibition of Mycobacterium tuberculosis Protein Antigen85C |
| 16 | Alexander Landgraf | Design and Synthesis of a Bifunctional Inhibitor Against Mycobacterium tuberculosis Antigen 85 Complex |
| 17 | Jieye Lin | 13C-13C Spin-Coupling Constants in Crystalline 13C-Labeled Saccharides: Conformational Effects Interrogated by Solid-State 13C NMR Spectroscopy |
| 18 | Kunli Liu and Mengxia Sun | Design, Synthesis and Screening of Carbohydrate Derivatives and Mimetics for Cancer Therapy |
| 19 | Shuai Meng | Mechanistic Investigations of β-Mannosylations via Cs2CO3-Mediated Anomeric O-Alkylation and Synthesis of Complex Biologically Significant Carbohydrate Molecules |
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20 |
Reagan Meredith | MA’AT Circular Statistics Software Development and Applications To Carbohydrate Structure Determination |
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21 |
Qingfeng Pan | An Unusual Glycosylation Side-Reaction and its Application in Glycan Synthesis |
| 22 | Rebecca Pan | Isolation of Sialyl Glycopeptide from Commercial Hen Egg Yolk Powder |
| 23 | Sherif Ramadan | Synthesis of Chondroitin Sulfate (CS) Oligosaccharide Library and CS Chain (24-mer) of Bikunin and its Anti-Inflammatory Activity |
| 24 | Melanie Shadrick | Stereocontrolled Synthesis of Galactosides Using Acid-Catalyzed Koenigs-Knorr Reaction |
| 25 | Ganesh Shrestha | Indolyl Thioimidates as New Building Blocks for Chemical Glycosylation |
| 26 | Anshupriya Si | Synthesis of Carbocyclic Maltose Derivatives Used as Potential Inhibitors of Mycobacterium tuberculosis GlgE |
| 27 | Alicyn Stothard | Trehalose Analogues Block Utilization of Trehalose by Hypervirulent Clostridium difficile |
| 28 | Zibin Tan and Hunter McFall-Boegeman | Engineering of Bacteriophage Qß for Use as a Conjugate Vaccine Platform |
| 29 | Tim Tetrault | Synthesis and Conformational Studies of O-Glycosidic Linkages in 13C-Labeled Complex-Type N-Glycans Constructed From a Labeled Man3GlcNAc2 Core |
| 30 | Radhika Thanvi | Synthesis of Potential Carbasugar-based Inhibitors of Mycobacterium tuberculosis GlgE |
| 31 | Prakash Thapa | Stereoselective Synthesis of 2,3-Diamino-2,3-Dideoxy-β-D-mannopyranosyl Uronates Existing in Various Bacterial Capsular Polysaccharides |
| 32 | Peng Wen | De Novo Synthesis of 3-Amino-2,3,6-Trideoxy Sugars |
| 33 | Mi-Kyung Yoon | Chemo-enzymatic Synthesis and NMR Spin-Spin Coupling Constant Measurements on Complex-Type N-Glycans |
| 34 | Weizhun Yang | Chemical Synthesis of Syndecan-4-Glycopeptide Bearing O-, N-sulfation and Multiple Aspartic Acids for Probing Impacts of the Glycan Chain and the Core Peptide on Biological Functions |
| 35 | Wenhui Zhang | Inter-residue Hydrogen Bonding Does Not Determine the Conformation and Dynamics of β-(1→4) O-Glycosidic Linkages In Aqueous Solution |
| 36 | Yu Zhao | Sialylation Status and Mechanical Properties of THP-1 Macrophages upon LPS Stimulation |
| 37 | Nikolas Kambitsis | Synthesis of Next Generation FRET Probes for Real-Time Monitoring of Glycolipid Processing in Mycobacteria |
| 38 | Amendra Liyanarachchi | Incorporating PDMAB to Monosaccharides as a Microwave Labile Protecting Group to Facilitate Neutral Glycosylation |
| 39 | Shanika Gamage | Development of Neutral Glycosylation Protocol using Novel Microwave Labile Functional Handle PDMAB/PDEAB through O-alkylation Strategy |