MCGS Technical Program

Technical Program

 

All meeting events will occur in Room 105 and the Galleria of the Jordan Hall of Science, University of Notre Dame.

A PDF copy of the technical program can be accessed here MCGS Technical Program. Printed copies of the technical program will be distributed at the symposium.

The draft for the meal plan can be accessed here MCGS_Meal_Plan_DRAFT.

 

Schedule of Events

 

Friday, September 20, 2019

 

4:30 – 6:15 pm 

Meeting Registration; Poster Setup

Jordan Hall of Science – Galleria

 

Session I

Jordan Hall of Science – Room 105

Chair: Linda Hsieh-Wilson (CalTech)

6:25 – 6:30 pm

Introductory Remarks

Anthony S. Serianni

6:30 – 7:00 pm

Dr. Richard D. Cummings

Professor, Department of Surgery, Harvard University

Recognizing Sugars – Chemical Biology and Physiological Roles

7:00 – 7:15 pm

Nicholas Banahene

Student, Swarts Lab, Department of Chemistry and Biochemistry, Central Michigan University

O-Acylated Trehalose Analogues for Probing Cellular Processes and Components in Corynebacterineae

7:15 – 7:45 pm

Dr. Joseph J. Barchi Jr.

Senior Scientist, Center for Cancer Research, National Cancer Institute

The Thomsen Friedenreich Tumor-Associated Carbohydrate Antigen in Anticancer Drug Discovery

7:45 – 8:15 pm

Break; Poster Session

Jordan Hall of Science – Galleria

8:15 – 8:30 pm

Shuyao Lang

Student, Huang Lab, Department of Chemistry and Biomedical Engineering, Michigan State University

Glyco-engineering of Natural Killers Cells with CD22 Ligands for Effective Anti-Cancer Immunotherapy

8:30 – 9:00 pm

Dr. Roger A. Laine

Department of Biological Sciences, Department of Chemistry, Louisiana State University

Chief Executive Officer, TumorEnd, LLC.

Polysaccharides as Tumor Therapeutics, 1868-2019

9:00 pm

Reception; Poster Session

Jordan Hall of Science – Galleria

 

Saturday, September 21, 2019

 

7:30 – 8:15 am

Continental Breakfast (Jordan Hall)

Jordan Hall of Science – Galleria

 

Session II

Jordan Hall of Science – Room 105

Chair: Peter Andreana (University of Toledo)

8:15 – 8:30 am

Dr. Mary Prorok

Assistant Chair, Department of Chemistry and Biochemistry, University of Notre Dame

The Evolution of Laboratory Safety at Notre Dame

8:30 – 9:00 am

Dr. Linda Hsieh-Wilson

Professor, Division of Chemistry and Chemical Engineering, California Institute of Technology

Streamlined Methods for the Synthesis and Study of Heparin Sulfate Oligosaccharides

9:00 – 9:15 am

Jicheng Zhang

Student, Huang Lab, Department of Chemistry, Michigan State University

Chemical Synthesis of Heparin Like Head to Tail Multimers

9:15 – 9:45 am

Dr. Norman J. Dovichi

Professor, Department of Chemistry and Biochemistry, University of Notre Dame

Capillary Electrophoresis-Mass Spectrometry Reveals the N-Glycome During Vertebrate Embryogenesis

9:45 – 10:45 am

Break; Poster Session

Jordan Hall of Science – Galleria

10:45 – 11:00 am

Mithila D. Bandara

Student, Demchenko Lab, Department of Chemistry and Biochemistry, University of Missouri-St. Louis

Synthesis of Human Milk Oligosaccharides

11:00 – 11:30 am

Dr. Jacquelyn Gervay-Hague

Professor, Department of Chemistry, University of California, Davis

Protecting Group Modulation of Glycosyl Iodide Reactivity to Yield Metabolic Probes of Interspecies Chemical Communication

11:30 – 11:45 am

Sonia Tomar

Student, Sun Lab, Department of Chemistry, Cleveland State University

Investigation of Substrate Specificity of Sialidases with Membrane Mimetic Glycoconjugates

11:45 am – 1:45 pm

Lunch; Poster Session

Jordan Hall of Science – Galleria

1:00 – 1:45 pm

PI Meeting

Jordan Hall of Science – Reading Room

 

Session III

Jordan Hall of Science – Room 105

Chair: Jacquelyn Gervay-Hague (UC-Davis)

1:45 – 2:15 pm

Dr. Shahriar Mobashery

Professor, Department of Chemistry and Biochemistry, University of Notre Dame

Cell-Wall Recycling in Pseudomonas aeruginosa and the Nexus to Antibiotic Resistance

2:15 – 2:30 pm

Jia Gao

Student, Huang Lab, Department of Chemistry, Michigan State University

Chemoenzymatic Synthesis of Heparan Sulfate Glycopeptide Mimetics and Evaluation of Its Biological Functions

2:30 – 3:00 pm

Dr. Ming Tien

Professor, Department of Biochemistry and Molecular Biology, The Pennsylvania State University

Initiation, Elongation and Termination of Bacterial Cellulose Synthesis

3:00 – 3:30 pm

Break; Poster Session

Jordan Hall of Science – Galleria

3:30 – 3:45 pm

Dr. Jiaoyang Jiang

Associate Professor, Pharmaceutical Sciences Division, University of Wisconsin-Madison

Targeted Covalent Inhibition of O-GlcNAc Transferase in Cells

3:45 – 4:15 pm

Dr. Darón I. Freedberg

Research Chemist, U.S. Food & Drug Administration

Hydrogen Bonding in the Conformations of Glycans

4:15 – 4:30 pm

Matteo Panza

Student, Demchenko Lab, Department of Chemistry and Biochemistry, University of Missouri-St. Louis

HPLC-Based Oligosaccharide Synthesis: Entirely Automated Glycan Synthesis

4:30 – 5:00 pm

Dr. Robert J. Woods

Professor, Department of Biochemistry and Molecular Biology, Department of Chemistry, Complex Carbohydrate Research Center, University of Georgia

Glycomimetics to Inhibit Influenza Infection

5:00 – 5:30 pm

Awards; Concluding Remarks

5:30 – 6:15 pm

Poster Breakdown

6:15 pm

Dinner

Jordan Hall of Science – Galleria

 

List of Posters

1 Catherine Alex Hydrogen-Bond-Mediated Aglycone Delivery for Stereocontrolled β-Mannosylation
2 Aathmaja Anandhi Rangarajan Characterizing Spacial and Metabolic Relationships between the Gut Microbes Bacteriodes thetaiotaomicron and Ruminococcus bromii during Resistant Startch Degradation
3 Luis Avila Elucidating the Interactome of the Lytic Transglycosylase RlpA of Pseudomonas aeruginosa
4 Kedar Baryal Synthesis of a Comprehensive Heparan Sulfate Tetrasaccharide Library
5 Bishwa Bhetuwal Cs2CO3-Mediated Anomeric O-Alkylation: Stereoselective Synthesis of β-Mannosamines and Synthesis of Representative Bacterial Capsular Polysaccharides
6 Stephanie Blaszczyk Chiral Benzotetramisole-Catalyzed Site-Selective Acylation of Carbohydrates Directed by Anomeric S-Adamantyl Group
7 Ka Keung Chan Synthesis and Evaluation of Chain-End Functionalized N-Glycan Polymers as Biomimetic Macro-Glycoligands
8 Shivangi Chugh and Zahra Rashidi Exploring Bacteriophage Qβ Virus-like Particle as a Platform to Design Vaccines for Various Applications
9 Vinod Kumar Gattoji Synthesis of Entirely Carbohydrate Immunogen GD2-PS A1 and Production of Anti-GD2 mABs
10 Laurent Geffroy Dynamics of Three Carbohydrate Utilization System Glycoside Hydrolases Probed by Single-Molecule Fluorescence Measurements
11 Dana Gepford Synthesis of Fluorogenic Trehalose and Trehalose Monomycolate Analogues for the Detection of Mycobacteria
12 Jessica Groenevelt Pharmacological Targeting of O-GlcNAc Readers via Glycopeptide Mimetics
13 Ishani Hettiarachchi Synthesis of Trisaccharide Oligomer of Salmonella E1 Capsular Polysaccharide via Anomeric O-Alkylation
14 Joseph Keil Site-Specific Glyco-Engineering of Recombinant Thrombomodulin
15 Saniya Shehbaz Khan Synthesis of Tetrahydrolipstatin Congerners for Inhibition of Mycobacterium tuberculosis Protein Antigen85C
16 Alexander Landgraf Design and Synthesis of a Bifunctional Inhibitor Against Mycobacterium tuberculosis Antigen 85 Complex
17 Jieye Lin 13C-13C Spin-Coupling Constants in Crystalline 13C-Labeled Saccharides: Conformational Effects Interrogated by Solid-State 13C NMR Spectroscopy
18 Kunli Liu and Mengxia Sun Design, Synthesis and Screening of Carbohydrate Derivatives and Mimetics for Cancer Therapy
19 Shuai Meng Mechanistic Investigations of β-Mannosylations via Cs2CO3-Mediated Anomeric O-Alkylation and Synthesis of Complex Biologically Significant Carbohydrate Molecules
 

20

Reagan Meredith MA’AT Circular Statistics Software Development and Applications To Carbohydrate Structure Determination
 

21

Qingfeng Pan An Unusual Glycosylation Side-Reaction and its Application in Glycan Synthesis
22 Rebecca Pan Isolation of Sialyl Glycopeptide from Commercial Hen Egg Yolk Powder
23 Sherif Ramadan Synthesis of Chondroitin Sulfate (CS) Oligosaccharide Library and CS Chain (24-mer) of Bikunin and its Anti-Inflammatory Activity
24 Melanie Shadrick Stereocontrolled Synthesis of Galactosides Using Acid-Catalyzed Koenigs-Knorr Reaction
25 Ganesh Shrestha Indolyl Thioimidates as New Building Blocks for Chemical Glycosylation
26 Anshupriya Si Synthesis of Carbocyclic Maltose Derivatives Used as Potential Inhibitors of Mycobacterium tuberculosis GlgE
27 Alicyn Stothard Trehalose Analogues Block Utilization of Trehalose by Hypervirulent Clostridium difficile
28 Zibin Tan and Hunter McFall-Boegeman Engineering of Bacteriophage Qß for Use as a Conjugate Vaccine Platform
29 Tim Tetrault Synthesis and Conformational Studies of O-Glycosidic Linkages in 13C-Labeled Complex-Type N-Glycans Constructed From a Labeled Man3GlcNAc2 Core
30 Radhika Thanvi Synthesis of Potential Carbasugar-based Inhibitors of Mycobacterium tuberculosis GlgE
31 Prakash Thapa Stereoselective Synthesis of 2,3-Diamino-2,3-Dideoxy-β-D-mannopyranosyl Uronates Existing in Various Bacterial Capsular Polysaccharides
32 Peng Wen De Novo Synthesis of 3-Amino-2,3,6-Trideoxy Sugars
33 Mi-Kyung Yoon Chemo-enzymatic Synthesis and NMR Spin-Spin Coupling Constant Measurements on Complex-Type N-Glycans
34 Weizhun Yang Chemical Synthesis of Syndecan-4-Glycopeptide Bearing O-, N-sulfation and Multiple Aspartic Acids for Probing Impacts of the Glycan Chain and the Core Peptide on Biological Functions
35 Wenhui Zhang Inter-residue Hydrogen Bonding Does Not Determine the Conformation and Dynamics of β-(1→4) O-Glycosidic Linkages In Aqueous Solution
36 Yu Zhao Sialylation Status and Mechanical Properties of THP-1 Macrophages upon LPS Stimulation
37 Nikolas Kambitsis Synthesis of Next Generation FRET Probes for Real-Time Monitoring of Glycolipid Processing in Mycobacteria
38 Amendra Liyanarachchi Incorporating PDMAB to Monosaccharides as a Microwave Labile Protecting Group to Facilitate Neutral Glycosylation
39 Shanika Gamage Development of Neutral Glycosylation Protocol using Novel Microwave Labile Functional Handle PDMAB/PDEAB through O-alkylation Strategy