Publications

  • La Bella AA, Andersen MJ, Gervais NC, Molina JJ, Molesan A, Stuckey PV, Wensing L, Nobile CJ, Shapiro RS, Santiago-Tirado FH,* Flores-Mireles AL.* (2023) The catheterized bladder environment promotes Efg1- and Als1-dependent Candida albicans infection. Sci Adv. 9(9):eade7689. doi: 10.1126/sciadv.ade7689. *, co-corresponding authors.
  • Santiago-Tirado FH, Hurtaux T, Geddes-McAlister J, Nguyen D, Helms V, Doering TL, and Römisch K. (2023) The ER protein translocation channel subunit Sbh1 controls virulence of Cryptococcus neoformans. mBio 14(1):e0338422. doi: 10.1128/mbio.03384-22.
  • Gervais NC, La Bella AA, Wensing LF, Sharma J, Acquaviva V, Best M, Cadena López RO, Fogal M, Uthayakumar D, Chavez A, Santiago-Tirado F, Flores-Mireles AL, Shapiro RS. (2022) Development and applications of a CRISPR activation system for facile genetic overexpression in Candida albicans. G3: Genes|Genomes|Genetics, jkac301. doi: 10.1093/g3journal/jkac301.
  • Santiago-Burgos EJ, Stuckey PV, Santiago-Tirado FH. (2022) Real-time visualization of phagosomal pH manipulation by Cryptococcus neoformans in an immune signal-dependent way. Front Cell Infect Microbiol. 12:967486. doi: 10.3389/fcimb.2022.967486.
  • Winski CJ, Qian Y, Mobashery S, Santiago-Tirado FH. (2022) An Atypical ABC Transporter Is Involved in Antifungal Resistance and Host Interactions in the Pathogenic Fungus Cryptococcus neoformans. mBio 13(4):e0153922. doi: 10.1128/mbio.01539-22.
  • Santiago-Tirado FH. (2019) mSphere of Influence: the Power of Yeast Genetics Still Going Strong! mSphere 4(5). doi: 10.1128/mSphere.00647-19.
  • Santiago-Tirado FH, Klein RS, and Doering TL. (2019) An In Vitro Brain Endothelial Model for Studies of Cryptococcal Transmigration into the Central Nervous System. Curr Protoc Microbiol. 53(1):e78. doi: 10.1002/cpmc.78.
  • Santiago-Tirado FH, Onken MD, Klein RS, Cooper JA, and Doering TL. (2017) Trojan horse transit contributes to blood-brain barrier crossing of a eukaryotic pathogen. mBio 8 (1): e02183-16. doi: 10.1128/mBio.02183-16
  • Santiago-Tirado FH and Doering TL. (2017) False friends: Phagocytes as Trojan horses in microbial brain infections. PLoS Pathogens 13(12): e1006680. doi: 10.1371/journal.ppat.1006680
  • Gish SR, Maier EJ, Haynes BC, Santiago-Tirado FH, Srikanta DL, Ma CZ, Li LX, Williams M, Crouch EC, Khader SA, Brent MR, Doering TL. (2016) Computational Analysis Reveals a Key Regulator of Cryptococcal Virulence and Determinant of Host Response. mBio 7 (2): e00313-16. doi: 10.1128/mBio.00313-16.
  • Santiago-Tirado FH and Doering TL. (2016) All about that fat: Lipid modification of proteins in Cryptococcus neoformansJournal of Microbiology 54: 212-222. doi: 10.1007/s12275-016-5626-6
  • Santiago-Tirado FH, Peng T, Yang M, Hang HC, and Doering TL. (2015) A Single Protein S-acyl Transferase Acts through Diverse Substrates to Determine Cryptococcal Morphology, Stress Tolerance, and Pathogenic Outcome. PLoS Pathogens 11: e1004908. doi: 10.1371/journal.ppat.1004908
  • Kumar P, Heiss C, Santiago-Tirado FH, Black I, Azadi P, Doering TL. (2014) Pbx proteins in Cryptococcus neoformans cell wall remodeling and capsule assembly. Eukaryot Cell. 13 (5): 560-71. doi: 10.1128/EC.00290-13.
  • Srikanta D, Santiago-Tirado FH, Doering TL. (2014) Cryptococcus neoformans: historical curiosity to modern pathogen. Yeast. 31 (2): 47-60. doi: 10.1002/yea.2997.
  • Chernyakov, I., Santiago-Tirado, F., and Bretscher, A. (2013) Active segregation of yeast mitochondria by Myo2 is essential and mediated by Mmr1 and Ypt11. Current Biol. 23, 1818-1824. doi: 10.1016/j.cub.2013.07.053
  • Liu W, Santiago-Tirado FH, Bretscher A. (2012) Yeast formin Bni1p has multiple localization regions that function in polarized growth and spindle orientation. Mol Biol Cell 23 (3): 412-22. doi: 10.1091/mbc.E11-07-0631.
  • Santiago-Tirado FH, Bretscher A. (2011) Membrane-trafficking sorting hubs: cooperation between PI4P and small GTPases at the trans-Golgi network. Trends Cell Biol. 21 (9): 515-25. doi: 10.1016/j.tcb.2011.05.005.
  • Santiago-Tirado FH, Legesse-Miller A, Schott D, and Bretscher A. (2011) PI4P and Rab inputs collaborate in myosin-V-dependent transport of secretory compartments in yeast. Developmental Cell 20: 47-59. doi: 10.1016/j.devcel.2010.11.006
  • Legesse-Miller A, Zhang S, Santiago-Tirado FH, Van Pelt CK, Bretscher A. (2006) Regulated phosphorylation of budding yeast’s essential myosin V heavy chain, Myo2p. Mol Biol Cell 17 (4): 1812-21. doi: 10.1091/mbc.e05-09-0872.