Research Team

Dr. Juliane Hopf 

Departmental Affiliation: Civil & Environmental Engineering & Earth Sciences (CEEES)
Degree and university: Doctorate in Natural Sciences from the Friedrich-Schiller-Univerity Jena
Expertise:
Microbiology, biogeochemistry, interdisciplinary sciences, surface characterization, atomic force microscopy
Webpage:
https://www.linkedin.com/in/hopfjuliane/
Publications with us:
1. Nanoscale Adv., 2019,1, 4812-4826

2. Pharmaceuticals 2022, 15, 1216. https://doi.org/10.3390/ph15101216

3. Nanoscale Advances, 2024, DOI: 10.1039/D3NA00620D


Carlie Kudary (Berthiaume Institute for Precision Health Biomedical Technician)

Notre Dame Research Exemplary Recognition Award Recipient for FY’23

Departmental Affiliation: Berthiaume Institute for Precision Health
Degree and university:
BS in Biology (Pierre Laclede Honors) from University of Missouri- St. Louis ‘2021
Current Responsibilities:
Carlie works closely with the Berthiaume Institute for Precision Health Faculty Director, Associate Director of Research, other BIPH staff, and BIPH-affiliated faculty. She helps them execute BIPH laboratory research programs. Specific duties include supervising research associates in the institute’s lab space, training new research personnel on good lab practices, imparting lab-specific synthesis protocols and precautions for bio-sample handling, and optimizing sample characterization workflows.

Publications with us:
1. Nanoscale Advances, 2024, DOI: 10.1039/D3NA00620D

2. PLGA nanoparticles formulations loaded with antibiotics induce sustained and controlled antibiotics release for prolonged antibacterial action against MRSA, and Pseudomonas aeruginosa FRD1.  Military Medicine, 2024, Ms. No. MILMED-D-23-00750R1 (Accepted for Publication Feb 22, 2024)


Johanna Olesk (Bioengineering Graduate Student 2021 – 2023; MS Bioengineering ’23)

Materials Science and Engineering Fellow (2022-2023)

Departmental Affiliation: Bioengineering Graduate Program, Department of Chemical and Biomolecular Engineering (CBE)
Degree, Year and university: BSc in Bioengineering and Robotics from the University of Tartu (2021)
Expertise: Machine learning, synthetic biology, image processing, cell culture
Current Research:  Research focused on the optimized design of antimicrobial phage-mimicking core-shell nanoparticles using AI. The computer-designed nanoparticles are further synthesized in the laboratory and tested in vitro and in vivo against multi drug resistant bacteria such as MRSA, P.aeruginosa, A. Baumannii, K.pneumoniae..
Webpage: www.linkedin.com/in/johanna-olesk-5912571b7

Publications with us:
1. Nanoscale Advances, 2024, DOI: 10.1039/D3NA00620D


Olivia Sayani (ND 2027)

Departmental Affiliation: Chemical and Biomolecular Engineering
Degree Major:
Chemical Engineering (2027) Degree minor: Bioengineering
Current Research:
Olivia is working on antimicrobial phage-mimicking core-shell nanoparticles and testing against multi-drug resistant bacteria such as MRSA, P.aeruginosa, A. Baumannii, and K.pneumoniae. She will further explore culturing common skin bacteria with potential for pathogenicity (e.g., S. epidermidis, S. intermedius, C. acnes) and assess the antibacterial efficacy of the PhaNP coated implant materials under anerobic conditions.

Jack Lyu (ND 2026)

Departmental Affiliation: Department of Biological Sciences
Degree Major:
Biological Science(2026);
Current Research:
Jack is working on testing the anticancer efficacy of magnetoelectric nanoparticles loaded with chemotherapeutics against Triple-negative Breast Cancer Cells of different ethnic lineages and esophageal cancer cells.
Awards: 
NDnano undergraduate research fellow 2023 (NURF)

Kevin Armknecht (ND 2024)

Departmental Affiliation: Department of Chemical and Biomolecular Engineering
Degree Major:
Pre-Professional Studies(2024); Minor: Compassionate Care in Medicine; Minor: Poverty Studies
Current Research:
Kevin is working on antimicrobial phage-mimicking core-shell nanoparticles and testing against multi-drug resistant bacteria such as MRSA, P.aeruginosa, A. Baumannii, and K.pneumoniae. He is currently expanding the scope of the antibacterial activity against common skin bacteria with potential for pathogenicity (e.g., S. epidermidis, S. intermedius, C, acnes)
Awards: 
NDnano undergraduate research fellow 2023 (NURF)

Publications with us:
1. Nanoscale Advances, 2024, DOI: 10.1039/D3NA00620D

2. PLGA nanoparticles formulations loaded with antibiotics induce sustained and controlled antibiotics release for prolonged antibacterial action against MRSA, and Pseudomonas aeruginosa FRD1.  Military Medicine, 2024, Ms. No. MILMED-D-23-00750R1 (Accepted for Publication Feb 22, 2024)


Conor Sheehan (ND 2024)

Departmental Affiliation: Department of Chemistry and Biochemistry
Degree Major:
Chemistry and Biochemistry
Current Research:
Conor is working on immobilizing antimicrobial phage-mimicking core-shell nanoparticles on implant grade metals and testing them against multi-drug resistant bacteria such as MRSA, P.aeruginosa, A. Baumannii, K.pneumoniae.
Awards: NDnano undergraduate research fellow 2022 (NURF)

Publications with us:
1. Nanoscale Advances, 2024, DOI: 10.1039/D3NA00620D


Zach Bennett (ND 2023)

GE Aviation (2023)

Departmental Affiliation: Department of Aerospace and Mechanical Engineering
Degree Major:
Mechanical Engineering
Current Research:
Zach applies his Mechanical engineering training to synthesize and characterize magnetoelectric nanoparticles for use as label-free, cancer-targeting drug delivery nanocarriers. Zach has also spent considerable time mapping the magnetic field necessary to direct the nanoparticles to cancerous tissue and not healthy normal tissue. .

Publications with us:
1. Pharmaceuticals 2022, 15, 1216. https://doi.org/10.3390/ph15101216

2. Nanoscale Advances, 2024, DOI: 10.1039/D3NA00620D


Argerie Guevara (ND 2023)

Boston University Bioengineering Graduate Program (2023 Admit)

NSF REU at Penn State University (2022)

Departmental Affiliation: Department of Chemical and Biomolecular Imaging
Degree Major:
Chemical Engineering
Current Research:
Argerie is working on creating polymeric nanoparticles for the controlled and sustained release of drugs and antibiotics at the wound site. Applications include bandages that can be applied in an austere setting and keeping infection at bay for multiple days.
Awards: NDnano undergraduate research fellow 2021 (NURF)

Publications with us:
1. PLGA nanoparticles formulations loaded with antibiotics induce sustained and controlled antibiotics release for prolonged antibacterial action against MRSA, and Pseudomonas aeruginosa FRD1.  Military Medicine, 2024, Ms. No. MILMED-D-23-00750R1 (Accepted for Publication Feb 22, 2024)


Jordan Chang (ND 2022)

Holy Cross Seminary at Notre Dame (2027)

Departmental Affiliation: Department of Physics
Degree Major:
Physics in Medicine
Current Research:
Jordan worked on characterizing magnetoelectric silica nanoparticles as potential drug delivery systems in preclinical in vivo mouse models. Jordan was adept at synthesis and characterization of the nanoparticles. He utilized MRI and in vivo fluorescence for the mouse imaging.
Awards: NDnano undergraduate research fellow 2020 (NURF)

Webpage: https://nd.joinhandshake.com/users/20128895

Publications with us:
1. Pharmaceuticals 2022, 15, 1216. https://doi.org/10.3390/ph15101216


Emma Tam (ND 2020)

Thomas Jefferson University Medical College (2023 admit)

Fulbright English Teaching Assistant 2021-2022

Departmental Affiliation: College of Arts and Letters
Degree Major:
Visual Communication Design Major
Current Research:
Emma Tam worked on creating bioconjugated hybrid nanoparticles (organic-inorganic hybrid) to create beacons to direct immune cells to target cold tumor cells.
Awards: Da Vinci Fellow (2019)

Publications with us:
1. Pharmaceuticals 2022, 15, 1216. https://doi.org/10.3390/ph15101216


Stephanie Wallace (ND 2021)

University of Minnesota Medical College (2021 admit)

Departmental Affiliation: Department of Mathematics and Preprofessional Studies
Degree Major:
Mathematics on life-science concentration with Actuarial Minor
Current Research:
Stephanie worked on hybrid soft-polymer/metal-oxide nanoparticles to deliver therapeutic payloads to cancer cells specifically and not to healthy cells to avoid off-target toxicity.
Awards: NDnano undergraduate research fellow 2019 (NURF)

Publications with us:
1. Pharmaceuticals 2022, 15, 1216. https://doi.org/10.3390/ph15101216


Veronica Kalwatjys (ND 2020)

Loyola University Stritch School of Medicine -Chicago (2022 admit)

Departmental Affiliation: Department of Chemistry and Biochemistry
Degree:
Bachelor of Science; Biochemistry (Major), Liturgical music ministry (minor)
Current Research:
Veronica worked on assessing cytocompatibility of magnetoelectric silica nanoparticles on human cell lines.
Awards: CoS-Summer Undergraduate Research Fellow 2018 (CoS-SURF)

Publications: 

1. Nanoscale Adv., 2019,1, 4812-4826


Margo Waters (ND 2020)

Ohio State University Medical College (2020 admit)

Departmental Affiliation: Department of Preprofessional Studies
Degree Major:
Science-Business (2020)
Current Research:
Margo did the initial in vitro screening of magnetoelectric silica nanoparticles are cancer cell specific drug delivery vehicles to triple negative breast cancer cells, chemoresistant ovarian cancer cells, and metastatic prostate cancer cells. Margo also worked on optimizing workflow for the synthesis of silica nanoparticles and metal-oxide nanoparticles.
Awards: NDnano undergraduate research fellow 2018 (NURF); Inaugral Woodwards Family Endowment Fellow

Publications: 

1. Nanoscale Adv., 2019,1, 4812-4826

2. Pharmaceuticals 2022, 15, 1216. https://doi.org/10.3390/ph15101216