Category Archive: Fluorescence

May 01

CD133+ Cancer Stem Cells Role in Metastasis

Excited for the 2nd publication this year through collaborative efforts with Harper Cancer Research Institute’s Karen Dahl (Title: CD133 Promotes Adhesion to the Ovarian Cancer Metastatic Niche). I did the 3D confocal imaging that showed CD133+ ovarian cancer cells clearly penetrate the basal epithelial cells, pointing to metastatic potential of stem cell like cancer cells. Looking …

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Mar 06

6th Annual Advanced Diagnostics and Therapeutics (AD&T) Symposium – March 6, 2018

Undergraduate Research Assistant Margo Waters (Sophomore), at her first poster presentation. Margo synthesizes the anisotropic nanoparticles being used in the ongoing study looking into the applications of antimicrobial peptides@nanoparticles as surfactants on implant materials and medical devices. The project lead is Dr. Juliane Hopf and her undergraduate mentee is Veronica Kalwatjys. The work is in collaboration …

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Mar 05

Advancing Nanotechnology in Labs Across Notre Dame

2018 has been off to a good start. Please check out, “Super-resolution fluorescence microscopy by stepwise optical saturation” by Yide Zhang, P.D. Nallathamby, et al. https://lnkd.in/eCFdf6W I am proud to have supplied Yide with the fluorescent nanoparticle probes that he used in this proof of concept paper for a new super-resolution technique that he co-invented with …

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Nov 05

Dual Mode CT/Fluorescence Detectable Immunotargeted Nanoparticle Probes to Identify Self-Renewing Cancer Cells In Vivo

Statement of Purpose: The high mortality and poor prognosis for women diagnosed with ovarian cancer is mainly due to late diagnosis. Improved detection of primary tumors and recurring tumors after chemotherapy is, therefore, crucial to reduce ovarian cancer mortality and improve progression-free survival. However, current clinical screening and diagnostic imaging methods are limited by low …

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