Category Archive: Harper Cancer Research Institute

Aug 12

Real Men Wear Pink of Michiana

Here is my fundraising profile for the local chapter of the American Cancer Society. Introducing Real Men Wear Pink Candidate: Dr. Prakash Nallathamby from Harper Cancer Research Institute at Notre… Posted by Real Men Wear Pink of Michiana on Friday, August 9, 2019

Apr 08

Label-Free, Magnetic Nanocarrier based, Precision Combinatorial Chemotherapeutics Treatment Against Metastatic Cancer for Recurrence-Free Survival

╪1,3Margo Waters, ╪1,3Juliane Hopf, 1,3Paul Helquist, 2Vincent Jo Davisson, and 1,3Prakash. D. Nallathamby 1University of Notre Dame, Notre Dame USA; 2Purdue University, Lafayette, USA; 3NDnano, Notre Dame, USA ╪ Equal contributors The leading cause of fatalities in breast cancer is metastasis.1 To increase the success rate of metastasis-free survival, there is a need to tackle …

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Feb 14

American Cancer Society Seed Grant Awarded to us to Develop a Label-Free, Precise Chemotherapeutic Delivery to Metastatic Breast Cancer Cells In Vivo

We are extremely excited and thankful to the American Cancer Society and the Harper Cancer Research Institute for facilitating this seed grant for our work on label-free targeting of undruggable cancer cells. We intend to target non-targetable cancer cells by tuning the force exerted by label-free nanomaterials at the cell membrane to selectively permeabilize the …

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Feb 11

Read our review article on novel ‘Blue-sky’ future applications of nanoparticles in the Biomedical Field

Over the last two decades, nanotechnology has become one of the most dynamically evolving field of research. Various types of nanoparticles are widely exploited to extend our understanding of biological interactions at the molecular level. They are actively engaged in the biomedical research for imaging, biosensing, drug delivery and/or concurrent therapy. Recent progress on this …

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Nov 28

Nallathamby Laboratory in the Press for Novel Approach to CAR-T Therapy

Glad to see that our work on using nanoparticle-based ON-OFF switches for CAR-T cells therapy against solid tumors is getting positive traction in the local media. Here is my interview with Kylie Veleta of Inside Indiana business on what motivates us to keep pushing forward. The website is Indiana business focused. The interview was part …

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Aug 30

Nanoparticles that act as an “ON and OFF” switch to improve the safety and effectiveness of CAR-T cancer therapy

Always thankful for the internal support from Notre Dame Research #notredameresearch for supporting high risk-high gain projects such as mine. Here’s hoping that my faculty research support program initiation grant (FRSP-IG) #FRSP will pave the way for safer, more accessible CAR-T therapies and better quality of life for patients. https://research.nd.edu/news/developing-an-on-and-off-switch-for-breast-cancer-treatment/ The biggest bottle neck in Chimeric …

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Jul 02

Inaugural Woodward family endowment for excellence in NDNANO undergraduate research awarded to Margo Waters

Congratulations to Margo Waters of the Nallathamby lab for having being selected for the Inaugural Woodward family endowment for excellence in NDnano undergraduate research! Margo has been an exceptional contributor to advancing research on novel cancer therapeutics in our lab. You can check out more about what motivates her at https://research.nd.edu/news/inaugural-woodward-family-endowment-for-excellence-in-ndnano-undergraduate-research-awarded/

May 01

CD133+ Cancer Stem Cells Role in Metastasis

Excited for the 2nd publication this year through collaborative efforts with Harper Cancer Research Institute’s Karen Dahl (Title: CD133 Promotes Adhesion to the Ovarian Cancer Metastatic Niche). I did the 3D confocal imaging that showed CD133+ ovarian cancer cells clearly penetrate the basal epithelial cells, pointing to metastatic potential of stem cell like cancer cells. Looking …

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