Category Archive: multidrug resistance

Jan 29

Phage-Mimicking Antibacterial Nanoparticles Tackle Group A Streptococcal Infections In Vivo

We are excited to publish on our Phage-mimicking nanoparticles efficiently tackling Group A Streptococcus infections in mouse wound infection models in RSC Nanoscale Advances ( Thank you to Prof. Frank Castellino, Prof. Victoria Ploplis, and Deborah Donahue of the W.M. Keck Transgene Center for the in vivo studies. Thanks to Prof. Shaun Lee’s lab (Biology) …

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Oct 30

2nd Annual Berthiaume Institute for Precision Health’s Advisory Board Meeting

Great job by the Nallathamby lab (PDNANO) members Conor, Kevin and Carlie at presenting our work on antibacterials, and cancer therapeutics to the @ND_IPH advisory board! Great input from the advisory board members on possible collaborations and translational paths forward. #GoIrish#NDResearch#MDR#curecancer All three presenters have publications with us which formed the basis for these poster …

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Jul 07

Congratulations to Ms. Johanna Olesk on Defending her MS (Bioengineering) ’23 Thesis

Congratulations to Nallathamby lab’s @JohannaOlesk on successfully defending her Masters thesis for Bioengineering in Summer 2023. Her thesis was titled ” Phage-Mimicking Nanoparticles Conjugated with Antimicrobial Peptides and Polymers as an Alternative to Antibiotic Treatment.” She passed with unanimous consent. We wish her all the best in her future undertakings. #WomenInSTEM#notredame#GoIrish Special mention to all …

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Jun 17

Translational Science to Impact Public Health was our Goal at Techconnect 2023

We were excited to present our work titled, “Biomimetic, Antibiotic Free, Nanoparticles for Agent Agnostic Broad Spectrum Antimicrobial Action including ESKAPE Pathogens” [Abstract 557] at the  2023 TechConnect World Innovation Conference in National Harbor, MD (June 19-21, 2023), as part of the Precision Health and Diagnostics symposium. Our talk was well received. We got lots of useful …

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May 23

Medical Technology Enterprise Consortium’s (MTEC) 8th Annual Meeting- Richmond, VA (May 23-24, 2023)

Nallathamby group’s work on “Phage-mimicking, Broad-spectrum, antibacterial nanoparticles” was showcased at MTEC’s annual meeting in Richmond, Virginia. I am proud to represent Notre Dame and the Berthiaume Institute for Precision Health at the 8th annual meeting of MTEC to learn firsthand the medical needs of the DoD. Our focus on combating antimicrobial resistance using phage …

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May 01

Argerie Guevara (CBE’23) Successfully Defends her Undergraduate Thesis

Congratulations to @Argerie Guevara (CBE’23) for taking the thesis option in her undergraduate research and passing it with unanimous consensus today.  Her thesis was titled, “PLGA nanoparticles formulations loaded with antibiotics induce sustained and controlled antibiotics release for prolonged antibacterial action against MRSA, and Pseudomonas aeruginosa FRD1,” and is currently being peer-reviewed for publication. Argerie is currently …

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Jan 24

An Interesting Write-up on our Novel Class of Antibacterials to Tackle Antibiotic Resistant Pathogens

According to the World Health Organization, one of the biggest health threats around the world is antibiotic-resistant bacteria. Researchers at Notre Dame are working to combat this problem by developing a nanoparticle-based system. Please check out this press release written by Brandi Wampler, our science communication specialist at Notre Dame Research. The peer-reviewed publication …

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Nov 08

Fighting antibiotic resistant bacteria by skipping anitbiotics

Phage-mimicking antibacterial core–shell nanoparticles. Excited to have started publishing and filing for a patent on our antibiotic-free antimicrobial nanoparticles research. More to come in the following months! Thankful for the support from #notredame #ideacenter #antibioticresistance #ndnano #Advanceddiagnosticsandtherapeutics #ADandT #openaccess The increasing frequency of nosocomial infections caused by antibiotic-resistant microorganisms concurrent with the stagnant discovery of …

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Apr 03

Society for Biomaterials – Seattle 2019

I was in Seattle for the week at the Society for Biomaterials 2019 conference. Excited to have data from three projects in four sessions at SFB 2019. Thanks to CTSI-PDT (#CTSI), ACS-IRG(#americancersociety), NDnano, AD&T and HCRI for their crucial support for these projects. 1. Rapid-Fire oral Presentation on Wednesday on April 3, 2019, from 4:05 …

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Feb 14

Center for the Translational Sciences Indiana Awards us Seed Grant for an Innovative Antibiotic Free Nanotherapeutics to Combat Multi-drug Resistant Bacterial Infections

Biomedical research is at risk of losing the antibiotics vs. pathogens arms race. Pneumonia, tuberculosis, gonorrhea, and salmonellosis are becoming harder and sometimes impossible to treat due to the fast emergence and global spread of new antibiotic resistance. Without urgent action, we are heading for a post-antibiotic era, in which common infections and minor injuries …

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