Category Archive: AD&T Notre Dame

Nov 16

Nallathamby Lab is one of 20 Participants Invited to Present Phage-Mimicking Antibacterial Nanoparticle Prototype at the Inaugural Joint Innovation Medical Symposium (JIMS) at Pope Army Airfield/Fort Bragg (Nov 16-17, 2022)

In recent combat theaters, despite advances in treating critical injuries leading to higher survival rates, there has been an increase in the number of infections linked to trauma, particularly those caused by bacteria resistant to multiple drugs 1,2.  Research from the Trauma Infectious Disease Outcomes Study indicates that 27% of those evacuated with injuries develop …

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Mar 01

Science Outlets are More Actively Promoting Novel Technologies to Address Antibiotic-Resistant Bacteria and Antibiotic-Stewardship

Excited that our novel approach to tackling antibiotic resistance is gaining well-deserved publicity! We need outside the box thinking to tackle this problem. Juliane Hopf #advanceddoagnosticsandtherapeutics #notredame #antibioticresistance #nanotechnology #nanoscaleadvances  #pdnano #biomimetics #health #nanoparticles #nd Tackling antibiotic resistance: Phage-mimicking antibacterial core-shell nanoparticles could help by Brandi Wampler, University of Notre Dame Nanoparticle. Credit: P Nallathamby …

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Jan 24

An Interesting Write-up on our Novel Class of Antibacterials to Tackle Antibiotic Resistant Pathogens

According to the World Health Organization, one of the biggest health threats around the world is antibiotic-resistant bacteria. Researchers at Notre Dame are working to combat this problem by developing a nanoparticle-based system. Please check out this press release written by Brandi Wampler, our science communication specialist at Notre Dame Research. The peer-reviewed publication …

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Aug 08

Real Men Wear Pink in Michiana to Fight Breast Cancer

DONATE to ACS Online   Why We Wear Pink. Breast cancer affects everyone – it doesn’t matter if you’re a man or a woman. That’s why I’m stepping up to fight breast cancer with all I have. Since I’m in a position to make a difference within my community, I believe I have an obligation …

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Apr 08

Label-Free, Magnetic Nanocarrier based, Precision Combinatorial Chemotherapeutics Treatment Against Metastatic Cancer for Recurrence-Free Survival

╪1,3Margo Waters, ╪1,3Juliane Hopf, 1,3Paul Helquist, 2Vincent Jo Davisson, and 1,3Prakash. D. Nallathamby 1University of Notre Dame, Notre Dame USA; 2Purdue University, Lafayette, USA; 3NDnano, Notre Dame, USA ╪ Equal contributors The leading cause of fatalities in breast cancer is metastasis.1 To increase the success rate of metastasis-free survival, there is a need to tackle …

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Apr 03

Society for Biomaterials – Seattle 2019

I was in Seattle for the week at the Society for Biomaterials 2019 conference. Excited to have data from three projects in four sessions at SFB 2019. Thanks to CTSI-PDT (#CTSI), ACS-IRG(#americancersociety), NDnano, AD&T and HCRI for their crucial support for these projects. 1. Rapid-Fire oral Presentation on Wednesday on April 3, 2019, from 4:05 …

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Feb 14

Center for the Translational Sciences Indiana Awards us Seed Grant for an Innovative Antibiotic Free Nanotherapeutics to Combat Multi-drug Resistant Bacterial Infections

Biomedical research is at risk of losing the antibiotics vs. pathogens arms race. Pneumonia, tuberculosis, gonorrhea, and salmonellosis are becoming harder and sometimes impossible to treat due to the fast emergence and global spread of new antibiotic resistance. Without urgent action, we are heading for a post-antibiotic era, in which common infections and minor injuries …

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Feb 14

American Cancer Society Seed Grant Awarded to us to Develop a Label-Free, Precise Chemotherapeutic Delivery to Metastatic Breast Cancer Cells In Vivo

We are extremely excited and thankful to the American Cancer Society and the Harper Cancer Research Institute for facilitating this seed grant for our work on label-free targeting of undruggable cancer cells. We intend to target non-targetable cancer cells by tuning the force exerted by label-free nanomaterials at the cell membrane to selectively permeabilize the …

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Feb 11

Read our review article on novel ‘Blue-sky’ future applications of nanoparticles in the Biomedical Field

Over the last two decades, nanotechnology has become one of the most dynamically evolving field of research. Various types of nanoparticles are widely exploited to extend our understanding of biological interactions at the molecular level. They are actively engaged in the biomedical research for imaging, biosensing, drug delivery and/or concurrent therapy. Recent progress on this …

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Aug 30

Nanoparticles that act as an “ON and OFF” switch to improve the safety and effectiveness of CAR-T cancer therapy

Always thankful for the internal support from Notre Dame Research #notredameresearch for supporting high risk-high gain projects such as mine. Here’s hoping that my faculty research support program initiation grant (FRSP-IG) #FRSP will pave the way for safer, more accessible CAR-T therapies and better quality of life for patients. The biggest bottle neck in Chimeric …

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