Nov 16
In recent combat theaters, despite advances in treating critical injuries leading to higher survival rates, there has been an increase in the number of infections linked to trauma, particularly those caused by bacteria resistant to multiple drugs 1,2. Research from the Trauma Infectious Disease Outcomes Study indicates that 27% of those evacuated with injuries develop …
Sep 16
We are losing in an antibiotic arms race with bacteria due to the emergence and global spread of new antibiotic resistance mechanisms.1,2 At current rates of antibiotics discovery and development we will eventually lose to antibiotic-resistant strains, and by 2050, antibiotics resistant strains of bacteria will kill more patients per year than all cancers combined. …
May 14
Our research looks at the basic mechanism of drug resistance in bacteria or cancer cells and then we work on translational solutions to combat these problems. Our approach felt validated at this meeting where we networked with industry end-users as well as disease-on-a chip modeling academicians.
Jan 09
Virtually presented our lab’s research on tackling two pressing problems in biomedical research at the Society for Biomaterials/ Japanese Society for Biomaterials joint Symposium in Honolulu, Hawaii. (January 8-10, 2022). I am presenting our research on broad-spectrum antibiotic-free antibacterials to combat multi-drug resistant bacterial infections. Oral Presentation Session: Session 1: Bioglasses/Ceramics/Other Hard Materials2:37 – 2:52 …
Sep 02
The University of Notre Dame’s Institute for Precision Health (IPH) has awarded funding to researchers spanning multiple departments at the University, as well as to colleagues at partner schools. IPH awarded proposals with two types of funding: seed grants, which provide funding for high-risk, high-reward research ideas, and harvest grants, which help researchers expand on established projects or pursue …
Mar 01
Excited that our novel approach to tackling antibiotic resistance is gaining well-deserved publicity! We need outside the box thinking to tackle this problem. Juliane Hopf #advanceddoagnosticsandtherapeutics #notredame #antibioticresistance #nanotechnology #nanoscaleadvances #pdnano #biomimetics #health #nanoparticles #nd https://phys.org/news/2020-01-tackling-antibiotic-resistance-phage-mimicking-antibacterial.html Tackling antibiotic resistance: Phage-mimicking antibacterial core-shell nanoparticles could help by Brandi Wampler, University of Notre Dame Nanoparticle. Credit: P Nallathamby …
Jan 24
According to the World Health Organization, one of the biggest health threats around the world is antibiotic-resistant bacteria. Researchers at Notre Dame are working to combat this problem by developing a nanoparticle-based system. Please check out this press release written by Brandi Wampler, our science communication specialist at Notre Dame Research. https://news.nd.edu/news/new-technology-could-help-tackle-antibiotic-resistance/ The peer-reviewed publication …
Nov 08
Phage-mimicking antibacterial core–shell nanoparticles. Excited to have started publishing and filing for a patent on our antibiotic-free antimicrobial nanoparticles research. More to come in the following months! Thankful for the support from #notredame #ideacenter #antibioticresistance #ndnano #Advanceddiagnosticsandtherapeutics #ADandT #openaccess The increasing frequency of nosocomial infections caused by antibiotic-resistant microorganisms concurrent with the stagnant discovery of …
Feb 14
Biomedical research is at risk of losing the antibiotics vs. pathogens arms race. Pneumonia, tuberculosis, gonorrhea, and salmonellosis are becoming harder and sometimes impossible to treat due to the fast emergence and global spread of new antibiotic resistance. Without urgent action, we are heading for a post-antibiotic era, in which common infections and minor injuries …
May 04
The poster presented by the undergraduate researchers (Margo Waters and Veronica Kalwatjys), explaining their work on a rationally designed, modular antimicrobial nanoparticle system was well received at COS-JAM 2018. Margo worked on the synthesis of the antimicrobial nanoparticles. Veronica has started testing the antimicrobial properties of these nanoparticles under the direction of Dr. Juliane Hopf. …
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