Apr 08
╪1,3Margo Waters, ╪1,3Juliane Hopf, 1,3Paul Helquist, 2Vincent Jo Davisson, and 1,3Prakash. D. Nallathamby 1University of Notre Dame, Notre Dame USA; 2Purdue University, Lafayette, USA; 3NDnano, Notre Dame, USA ╪ Equal contributors The leading cause of fatalities in breast cancer is metastasis.1 To increase the success rate of metastasis-free survival, there is a need to tackle …
Apr 03
I was in Seattle for the week at the Society for Biomaterials 2019 conference. Excited to have data from three projects in four sessions at SFB 2019. Thanks to CTSI-PDT (#CTSI), ACS-IRG(#americancersociety), NDnano, AD&T and HCRI for their crucial support for these projects. 1. Rapid-Fire oral Presentation on Wednesday on April 3, 2019, from 4:05 …
Feb 14
Biomedical research is at risk of losing the antibiotics vs. pathogens arms race. Pneumonia, tuberculosis, gonorrhea, and salmonellosis are becoming harder and sometimes impossible to treat due to the fast emergence and global spread of new antibiotic resistance. Without urgent action, we are heading for a post-antibiotic era, in which common infections and minor injuries …
Feb 14
We are extremely excited and thankful to the American Cancer Society and the Harper Cancer Research Institute for facilitating this seed grant for our work on label-free targeting of undruggable cancer cells. We intend to target non-targetable cancer cells by tuning the force exerted by label-free nanomaterials at the cell membrane to selectively permeabilize the …
Feb 11
Over the last two decades, nanotechnology has become one of the most dynamically evolving field of research. Various types of nanoparticles are widely exploited to extend our understanding of biological interactions at the molecular level. They are actively engaged in the biomedical research for imaging, biosensing, drug delivery and/or concurrent therapy. Recent progress on this …
Nov 28
Glad to see that our work on using nanoparticle-based ON-OFF switches for CAR-T cells therapy against solid tumors is getting positive traction in the local media. Here is my interview with Kylie Veleta of Inside Indiana business on what motivates us to keep pushing forward. The website is Indiana business focused. The interview was part …
May 14
TechConnect #techconnect keeps getting better every year! Anaheim was a great location, with a good mix of entrepreneurs and investors! Looking forward to the next one in Boston in May 2019. I chaired a very engaging panel of experts who elaborated on the biggest problem facing the industrial production of uniform nanoparticles. I showcased Notre …
May 04
The poster presented by the undergraduate researchers (Margo Waters and Veronica Kalwatjys), explaining their work on a rationally designed, modular antimicrobial nanoparticle system was well received at COS-JAM 2018. Margo worked on the synthesis of the antimicrobial nanoparticles. Veronica has started testing the antimicrobial properties of these nanoparticles under the direction of Dr. Juliane Hopf. …
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