Category Archive: Berthiaume Institute for Precision Health

Feb 14

American Cancer Society Seed Grant Awarded to us to Develop a Label-Free, Precise Chemotherapeutic Delivery to Metastatic Breast Cancer Cells In Vivo

We are extremely excited and thankful to the American Cancer Society and the Harper Cancer Research Institute for facilitating this seed grant for our work on label-free targeting of undruggable cancer cells. We intend to target non-targetable cancer cells by tuning the force exerted by label-free nanomaterials at the cell membrane to selectively permeabilize the …

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Feb 11

Read our review article on novel ‘Blue-sky’ future applications of nanoparticles in the Biomedical Field

Over the last two decades, nanotechnology has become one of the most dynamically evolving field of research. Various types of nanoparticles are widely exploited to extend our understanding of biological interactions at the molecular level. They are actively engaged in the biomedical research for imaging, biosensing, drug delivery and/or concurrent therapy. Recent progress on this …

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Nov 28

Nallathamby Laboratory in the Press for Novel Approach to CAR-T Therapy

Glad to see that our work on using nanoparticle-based ON-OFF switches for CAR-T cells therapy against solid tumors is getting positive traction in the local media. Here is my interview with Kylie Veleta of Inside Indiana business on what motivates us to keep pushing forward. The website is Indiana business focused. The interview was part …

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Aug 30

Nanoparticles that act as an “ON and OFF” switch to improve the safety and effectiveness of CAR-T cancer therapy

Always thankful for the internal support from Notre Dame Research #notredameresearch for supporting high risk-high gain projects such as mine. Here’s hoping that my faculty research support program initiation grant (FRSP-IG) #FRSP will pave the way for safer, more accessible CAR-T therapies and better quality of life for patients. https://research.nd.edu/news/developing-an-on-and-off-switch-for-breast-cancer-treatment/ The biggest bottle neck in Chimeric …

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Jul 02

Inaugural Woodward family endowment for excellence in NDNANO undergraduate research awarded to Margo Waters

Congratulations to Margo Waters of the Nallathamby lab for having being selected for the Inaugural Woodward family endowment for excellence in NDnano undergraduate research! Margo has been an exceptional contributor to advancing research on novel cancer therapeutics in our lab. You can check out more about what motivates her at https://research.nd.edu/news/inaugural-woodward-family-endowment-for-excellence-in-ndnano-undergraduate-research-awarded/

May 14

TechConnect 2018 an SBIR/STTR Haven

TechConnect #techconnect keeps getting better every year! Anaheim was a great location, with a good mix of entrepreneurs and investors! Looking forward to the next one in Boston in May 2019. I chaired a very engaging panel of experts who elaborated on the biggest problem facing the industrial production of uniform nanoparticles. I showcased Notre …

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May 04

College of Science Joint Annual Meeting (CoS-JAM) Poster Presentation (May 4, 2018)

The poster presented by the undergraduate researchers (Margo Waters and Veronica Kalwatjys), explaining their work on a rationally designed, modular antimicrobial nanoparticle system was well received at COS-JAM 2018. Margo worked on the synthesis of the antimicrobial nanoparticles. Veronica has started testing the antimicrobial properties of these nanoparticles under the direction of Dr. Juliane Hopf. …

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May 01

CD133+ Cancer Stem Cells Role in Metastasis

Excited for the 2nd publication this year through collaborative efforts with Harper Cancer Research Institute’s Karen Dahl (Title: CD133 Promotes Adhesion to the Ovarian Cancer Metastatic Niche). I did the 3D confocal imaging that showed CD133+ ovarian cancer cells clearly penetrate the basal epithelial cells, pointing to metastatic potential of stem cell like cancer cells. Looking …

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Apr 01

MRS 2018 Spring Symposium,

I will be at MRS 2018 from April 1 to April 5 presenting my work on novel cancer therapeutics Title: Biocompatible, Radiotherapeutic Hafnium Oxide Nanoparticle Imaging Probes Prepared Using a Novel Templated Synthesis Abstract Control ID: # 2884959 Paper # NM05.01.05 Presentation Date: April 2, 2018 Presentation Time: 9:30 AM to 9:45 AM Location: PCC …

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Mar 21

ND-ECI Seminar with NDnano: Environmental Applications and Implications of Engineered Nanomaterials (March 21, 2018)

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