Cramping My Style: The Biomechanics Behind Period Pain

woman dressed in red lying in a pool of red fabric, representing blood

Imagine this: you’re jolted awake in the dead of night, disoriented and feeling a sharp, relentless pain radiating through your lower abdomen. Glancing at the clock, it’s only 3 a.m., but you already know the culprit. Your period has arrived—along with the familiar, sometimes debilitating cramps that will have you reaching for ibuprofen every few hours just to make it through the day. For as high as 45-95% of people who menstruate, this monthly pain feels inevitable, with studies showing that dysmenorrhea is one of the most common gynecological conditions. In this post, we’ll explore the biomechanics of period cramps, diving into what’s causing that pain, how your muscles and nerves are involved, and ways to find relief. 

The uterus, a pear-shaped, thick-walled organ, plays a central role in the female reproductive system, undergoing remarkable changes to support reproduction. It is the site where an embryo implants, grows, and eventually is delivered. Even when not pregnant, the uterus experiences various morphological changes throughout each menstrual cycle—typically lasting about 28 days—caused by changing levels of hormones like estrogen and progesterone produced by the ovaries. Research published in the Korean Journal of Family Medicine reveals the first few days of the cycle, these hormonal shifts initiate the process that leads to menstruation, the process through which the lining of the uterine wall, known as endometrial lining, is shredded and expelled through the vagina if a fertilized egg cell is not implanted to begin pregnancy. This expulsion of the broken down endometrial lining is made possible via contractions in the thick, muscular walls of the uterus. These uterine contractions are not only crucial for shedding the endometrial lining but are also the primary source of menstrual cramps. Understanding how and why these contractions occur—and the intense sensations they create—gives insight into the biomechanics of period pain. 

Anatomical images of the human uterus. On the left side is a sideways view, and the right side features a front view.
General anatomy of the uterus. Taken from Myers and Elad. https://doi.org/10.1002/wsbm.1388

Research published by the New York Academy of Sciences shows that throughout the menstrual cycle, the uterus undergoes regular, mild contractions that typically go unnoticed. However, during the first few days of menstruation, the intensity and frequency of these contractions increase significantly, often resulting in pain. This surge in contractions is triggered by a drop in progesterone levels and a corresponding rise in prostaglandins, hormone-like compounds that regulate several bodily functions including inflammation, pain, and muscle contractions. These elevated prostaglandin levels cause stronger uterine contractions and vasoconstriction, or the narrowing of blood vessels as the uterine muscles tighten around them. This constriction limits blood flow to the uterus, causing uterine ischemia—a state where the oxygen and nutrient supply to the uterus is reduced due to the limited blood flow. The result of this is the hypersensitization of pain fibers, contributing to the painful cramping sensation in the pelvis and lower abdomen many experience, known in medical terms as primary dysmenorrhea (PD).

A graph showing the hormone levels during the menstrual cycle. Progesterone is low around day 0 of the cycle.
Graph showing the levels of different hormones during the menstrual cycle. Taken from Myers and Elad. https://doi.org/10.1002/wsbm.1388

PD is often accompanied by a range of symptoms beyond pelvic and abdominal pain, including headaches, backaches, fatigue, changes in sleep patterns, and gastrointestinal issues like constipation or diarrhea.  These physical symptoms frequently concur with psychological symptoms like anxiety and depression, which can vary in intensity depending on factors like age, genetics, overall health, and lifestyle.

As we can see, dysmenorrhea isn’t just an inconvenience—it can seriously impact daily life and overall well-being. Yet, despite its prevalence, it’s often brushed off as “just part of being a woman.” For those who deal with it, though, finding ways to manage the pain can make all the difference. Whether it’s reaching for pain relievers or hormonal contraceptives, or opting for non-medical remedies like a hot water bottle, some gentle yoga, or even a brisk walk, there are options to help ease the discomfort. At the end of the day, understanding what’s happening inside your body is the first step to finding relief. Because when it comes to period cramps, knowledge—and maybe a little heat—is definitely power.